Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.43 |
| ▸ | MTNR1A | P48039 | 4/20 | 0.42 |
| ▸ | MTNR1B | P49286 | 4/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | CES1 | P23141 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7093380 | 1.00 | NPSR1 (0.43) | NPSR1MTNR1AMTNR1BKMT2AALDH1A1 | |
| SCHEMBL7090105 | 0.85 | NPC1 (0.46) | NPSR1KMT2AALDH1A1HTTNPC1 | |
| SCHEMBL7090110 | 0.85 | NPC1 (0.46) | NPSR1KMT2AALDH1A1HTTNPC1 | |
| SCHEMBL7092979 | 0.83 | ALDH1A1 (0.42) | NPSR1KMT2AALDH1A1HTTNPC1 | |
| SCHEMBL7092976 | 0.83 | ALDH1A1 (0.42) | NPSR1KMT2AALDH1A1HTTNPC1 | |
| SCHEMBL7091213 | 0.73 | RAB9A (0.49) | KMT2AALDH1A1HTTNPC1POLB | |
| SCHEMBL28910418 | 0.73 | NPSR1 (0.50) | NPSR1KMT2AALDH1A1HTTNPC1 | |
| SCHEMBL19435735 | 0.72 | MTNR1A (0.43) | NPSR1MTNR1AMTNR1BKMT2AALDH1A1 | |
| SCHEMBL6648938 | 0.72 | AKR1C1 (0.50) | MTNR1AMTNR1BKMT2AALDH1A1HTT | |
| SCHEMBL19435736 | 0.72 | MTNR1A (0.43) | NPSR1MTNR1AMTNR1BKMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003082777-A2 | NOVEL GLUCOCORTICOID RECEPTOR LIGANDS | KARO BIO AB (SE) | 2003-10-09 | — | — | WO | claimed |
| WO-2003082777-A2 | NOVEL GLUCOCORTICOID RECEPTOR LIGANDS | KARO BIO AB (SE) | 2003-10-09 | — | — | WO | disclosed |