Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 15/20 | 0.81 |
| ▸ | KDR | P35968 | 5/20 | 0.65 |
| ▸ | RET | P07949 | 4/20 | 0.65 |
| ▸ | SRC | P12931 | 3/20 | 0.65 |
| ▸ | MAPT | P10636 | 4/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.64 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.64 |
| ▸ | MAPK14 | Q16539 | 3/20 | 0.64 |
| ▸ | FBP1 | P09467 | 3/20 | 0.64 |
| ▸ | EPHB2 | P29323 | 2/20 | 0.64 |
| ▸ | ABL1 | P00519 | 2/20 | 0.64 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.64 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.64 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.64 |
| ▸ | MKNK1 | Q9BUB5 | 2/20 | 0.64 |
| ▸ | ERBB2 | P04626 | 2/20 | 0.64 |
| ▸ | MAPK13 | O15264 | 2/20 | 0.64 |
| ▸ | MAPK12 | P53778 | 2/20 | 0.64 |
| ▸ | MAPK11 | Q15759 | 2/20 | 0.64 |
| ▸ | GAK | O14976 | 2/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7091704 | 0.89 | EGFR (1.00) | EGFRFBP1ERBB2ERBB4 | |
| SCHEMBL5569018 | 0.79 | KDR (1.00) | EGFRKDRRETSRCMAPT | |
| SCHEMBL31060707 | 0.79 | EGFR (1.00) | EGFRKDRRETSRCMAPT | |
| SCHEMBL5474772 | 0.79 | KDR (1.00) | EGFRKDRRETSRCMAPT | |
| SCHEMBL5482883 | 0.79 | EGFR (1.00) | EGFRKDRRETSRCMAPT | |
| SCHEMBL1257431 | 0.78 | EGFR (1.00) | EGFRKDRRETSRCMAPT | |
| SCHEMBL29515328 | 0.78 | EGFR (1.00) | EGFRKDRRETSRCMAPT | |
| SCHEMBL24714014 | 0.78 | RET (0.55) | EGFRKDRRETKIF5BRAF1 | |
| SCHEMBL1180103 | 0.78 | KDR (1.00) | EGFRKDRRETSRCMAPT | |
| SCHEMBL7123822 | 0.78 | EGFR (1.00) | EGFRKDRRETSRCMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030144308-A1 | Fructose 1,6-bisphosphatase inhibitors | BAUER PAUL H (US) | 2003-07-31 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030144308-A1 | Fructose 1,6-bisphosphatase inhibitors | FBP1, HK1, G6PC1 | EGFR 2906/4885KDR 3022/4885RET 2203/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.