Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.56 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.51 |
| ▸ | LTA4H | P09960 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.46 |
| ▸ | ACHE | P22303 | 1/20 | 0.44 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7097649 | 0.99 | EHMT2 (0.55) | EHMT2HRH3LTA4HPOLBPDE4D | |
| SCHEMBL7094017 | 0.89 | SYK (0.52) | EHMT2POLBACHE | |
| SCHEMBL7094760 | 0.82 | HRH3 (0.52) | EHMT2HRH3 | |
| SCHEMBL7094592 | 0.82 | HRH3 (0.54) | EHMT2HRH3LTA4H | |
| SCHEMBL7096511 | 0.82 | HRH3 (0.54) | EHMT2HRH3 | |
| SCHEMBL7095121 | 0.81 | RXFP1 (0.42) | EHMT2 | |
| SCHEMBL7094945 | 0.79 | HRH3 (0.51) | EHMT2HRH3LTA4H | |
| SCHEMBL7094490 | 0.79 | HRH3 (0.51) | EHMT2HRH3 | |
| Hydrochloric Acid SCHEMBL7092902 | 0.79 | MEN1 (0.40) | EHMT2POLB | |
| SCHEMBL5564105 | 0.78 | MAOA (0.49) | CHRNA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1309551-A1 | INDOLINE DERIVATIVES AS 5HT2C ANTAGONISTS | SMITHKLINE BEECHAM PLC (GB) | 2003-05-14 | — | — | EP | disclosed |
| WO-2002014273-A1 | INDOLINE DERIVATIVES AS 5HT2C ANTAGONISTS | SMITHKLINE BEECHAM P.L.C. (GB) | 2002-02-21 | — | — | WO | disclosed |