Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 3/20 | 0.43 |
| ▸ | CA2 | P00918 | 7/20 | 0.35 |
| ▸ | CA1 | P00915 | 4/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 4/20 | 0.34 |
| ▸ | CA12 | O43570 | 2/20 | 0.33 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.33 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.33 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | CTSL | P07711 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7093257 | 0.83 | MAPT (0.39) | CA2CA1LMNACA9CA12 | |
| SCHEMBL7093258 | 0.83 | MAPT (0.39) | CA2CA1LMNACA9CA12 | |
| SCHEMBL7093260 | 0.81 | CA2 (0.35) | LTA4HCA2CA1LMNACA9 | |
| SCHEMBL7089757 | 0.75 | CA2 (0.44) | CA2CA1LMNACA9CA12 | |
| SCHEMBL7089756 | 0.75 | CA2 (0.44) | CA2CA1LMNACA9CA12 | |
| SCHEMBL7092445 | 0.71 | NPFFR1 (0.39) | CA2CA1CA9CA12MAPT | |
| SCHEMBL29447511 | 0.69 | LTA4H (0.57) | LTA4HPSMB5 | |
| SCHEMBL7141370 | 0.68 | NPFFR1 (0.40) | CA2CA1CA9CA12MAPT | |
| SCHEMBL7092580 | 0.67 | CA2 (0.59) | CA2CA1LMNACA9CA12 | |
| SCHEMBL7092581 | 0.67 | CA2 (0.59) | CA2CA1LMNACA9CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003087127-A2 | ANTIMICROBIAL COMPOUNDS AGAINST STAPHYLOCOCCI, MYCOBACTERIA, AND OTHER INFECTIOUS AGENTS | EXEGENICS INC. (US) | 2003-10-23 | — | — | WO | disclosed |