Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | CASP3 | P42574 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | SENP8 | Q96LD8 | 2/20 | 0.38 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.38 |
| ▸ | SENP6 | Q9GZR1 | 2/20 | 0.38 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.38 |
| ▸ | RELA | Q04206 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.38 |
| ▸ | GABBR2 | O75899 | 1/20 | 0.36 |
| ▸ | GABBR1 | Q9UBS5 | 1/20 | 0.36 |
| ▸ | ERBB2 | P04626 | 3/20 | 0.36 |
| ▸ | EGFR | P00533 | 2/20 | 0.36 |
| ▸ | IGF1R | P08069 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 4/20 | 0.35 |
| ▸ | TP53 | P04637 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7093590 | 1.00 | ALDH1A1 (0.38) | ALDH1A1NPC1CASP3RAB9ASENP8 | |
| SCHEMBL7090188 | 0.85 | ERBB2 (0.38) | ALDH1A1RAB9AL3MBTL1ERBB2EGFR | |
| SCHEMBL7090186 | 0.85 | ERBB2 (0.38) | ALDH1A1RAB9AL3MBTL1ERBB2EGFR | |
| SCHEMBL7090165 | 0.84 | ERBB2 (0.41) | ALDH1A1NPC1CASP3RAB9ASENP8 | |
| SCHEMBL7090167 | 0.84 | ERBB2 (0.41) | ALDH1A1NPC1CASP3RAB9ASENP8 | |
| SCHEMBL7155129 | 0.79 | GABBR2 (0.44) | ALDH1A1NPC1CASP3RAB9ASENP8 | |
| SCHEMBL13656879 | 0.79 | GABBR2 (0.44) | ALDH1A1NPC1CASP3RAB9ASENP8 | |
| SCHEMBL6306524 | 0.73 | GABBR2 (0.44) | ALDH1A1NPC1CASP3RAB9ASENP8 | |
| SCHEMBL7090861 | 0.71 | NR1H3 (0.45) | ALDH1A1NPC1CASP3RAB9ASENP8 | |
| SCHEMBL7089170 | 0.70 | MAOA (0.47) | ALDH1A1MAPTMAOAMAOBLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030121113-A1 | Oxobenzofuranylide-dihydroindolone | NESVADBA PETER (CH) | 2003-07-03 | — | — | US | disclosed |
| US-6503937-B1 | Coloring agents for high molecular weight materials such as polymers | CIBA SPECIALTY CHEMICALS CORPORATION | 2003-01-07 | — | — | US | disclosed |
| EP-1123289-B1 | OXOBENZOFURANYLIDE-DIHYDROINDOLONES | CIBA SC HOLDING AG (CH) | 2002-11-27 | — | — | EP | disclosed |
| EP-1123289-A1 | OXOBENZOFURANYLIDE-DIHYDROINDOLONE | Ciba SC Holding AG (CH) | 2001-08-16 | — | — | EP | disclosed |
| WO-2000024736-A1 | OXOBENZOFURANYLIDE-DIHYDROINDOLONE | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 2000-05-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030121113-A1 | Oxobenzofuranylide-dihydroindolone | CYP1B1, CYP1A1, ECI1 | ALDH1A1 225/4885NPC1 2435/4885CASP3 1316/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.