Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | TRPM8 | Q7Z2W7 | 7/20 | 0.44 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.39 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.38 |
| ▸ | FPR2 | P25090 | 1/20 | 0.38 |
| ▸ | CNR1 | P21554 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7093909 | 0.89 | TRPM8 (0.51) | EPHX1TRPM8LMNAALOX5NR1I2 | |
| SCHEMBL7092758 | 0.86 | TRPM8 (0.41) | EPHX1MEN1KMT2ATRPM8ALDH1A1 | |
| SCHEMBL7090261 | 0.85 | KDM4E (0.47) | EPHX1TRPM8ALDH1A1ALOX5NR1I2 | |
| SCHEMBL7093895 | 0.84 | IDO1 (0.44) | EPHX1MEN1KMT2ATRPM8ALDH1A1 | |
| SCHEMBL7094118 | 0.78 | TRPM8 (0.43) | TRPM8NR1I2 | |
| SCHEMBL7093888 | 0.75 | CPN1 (0.46) | EPHX1TRPM8ALOX5NR1I2 | |
| SCHEMBL7094981 | 0.75 | NR3C2 (0.56) | KMT2ATRPM8ALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL28275848 | 0.74 | SRC (0.50) | TRPM8LMNAALOX5 | |
| SCHEMBL7758852 | 0.73 | MEN1 (0.77) | EPHX1MEN1KMT2AS1PR3HTR2A | |
| SCHEMBL4566801 | 0.71 | TRPM8 (0.53) | EPHX1TRPM8ALDH1A1LMNAALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003082777-A2 | NOVEL GLUCOCORTICOID RECEPTOR LIGANDS | KARO BIO AB (SE) | 2003-10-09 | — | — | WO | claimed |
| WO-2003082777-A2 | NOVEL GLUCOCORTICOID RECEPTOR LIGANDS | KARO BIO AB (SE) | 2003-10-09 | — | — | WO | disclosed |