Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | TRPM8 | Q7Z2W7 | 12/20 | 0.45 |
| ▸ | NR1I2 | O75469 | 2/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.39 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.39 |
| ▸ | CNR2 | P34972 | 2/20 | 0.38 |
| ▸ | CNR1 | P21554 | 1/20 | 0.38 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7093909 | 0.91 | TRPM8 (0.51) | CYP1A2CYP2D6TRPM8NR1I2ALOX5 | |
| SCHEMBL7094118 | 0.85 | TRPM8 (0.43) | TRPM8NR1I2 | |
| SCHEMBL7093905 | 0.85 | EPHX1 (0.47) | ALDH1A1TRPM8NR1I2ALOX5EPHX1 | |
| SCHEMBL7093888 | 0.83 | CPN1 (0.46) | TDP1TRPM8NR1I2ALOX5EPHX1 | |
| SCHEMBL7092758 | 0.78 | TRPM8 (0.41) | ALDH1A1TRPM8NR1I2EPHX1 | |
| SCHEMBL7094981 | 0.76 | NR3C2 (0.56) | KDM4EALDH1A1MAPTTRPM8 | |
| SCHEMBL7093895 | 0.76 | IDO1 (0.44) | ALDH1A1TRPM8NR1I2EPHX1 | |
| SCHEMBL28275848 | 0.75 | SRC (0.50) | CYP1A2CYP2D6TDP1L3MBTL1TRPM8 | |
| SCHEMBL4566801 | 0.72 | TRPM8 (0.53) | ALDH1A1MAPTTRPM8NR1I2ALOX5 | |
| SCHEMBL11823197 | 0.72 | ALDH1A1 (0.56) | KDM4EALDH1A1CYP1A2CYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003082777-A2 | NOVEL GLUCOCORTICOID RECEPTOR LIGANDS | KARO BIO AB (SE) | 2003-10-09 | — | — | WO | claimed |
| WO-2003082777-A2 | NOVEL GLUCOCORTICOID RECEPTOR LIGANDS | KARO BIO AB (SE) | 2003-10-09 | — | — | WO | disclosed |