Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPM8 | Q7Z2W7 | 11/20 | 0.41 |
| ▸ | PARP1 | P09874 | 1/20 | 0.41 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.41 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | IDO1 | P14902 | 1/20 | 0.40 |
| ▸ | TDO2 | P48775 | 1/20 | 0.40 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.38 |
| ▸ | RELA | Q04206 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7093895 | 0.92 | IDO1 (0.44) | TRPM8PARP1MTNR1AMTNR1BALDH1A1 | |
| SCHEMBL7093905 | 0.86 | EPHX1 (0.47) | TRPM8ALDH1A1NR1I2SMN1; SMN2EPHX1 | |
| SCHEMBL7093909 | 0.85 | TRPM8 (0.51) | TRPM8NR1I2SMN1; SMN2EPHX1 | |
| SCHEMBL7094118 | 0.83 | TRPM8 (0.43) | TRPM8NR1I2 | |
| SCHEMBL7093888 | 0.78 | CPN1 (0.46) | TRPM8NR1I2EPHX1 | |
| SCHEMBL7090261 | 0.78 | KDM4E (0.47) | TRPM8ALDH1A1NR1I2EPHX1 | |
| SCHEMBL7094549 | 0.75 | NR3C1 (0.52) | ALDH1A1SMN1; SMN2 | |
| SCHEMBL7093211 | 0.73 | NR3C1 (0.50) | ALDH1A1SMN1; SMN2 | |
| SCHEMBL7092760 | 0.72 | HTR2A (0.43) | MTNR1AMTNR1BALDH1A1IDO1TDO2 | |
| SCHEMBL16924260 | 0.72 | TRPM8 (0.76) | TRPM8ALDH1A1NR1I2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003082777-A2 | NOVEL GLUCOCORTICOID RECEPTOR LIGANDS | KARO BIO AB (SE) | 2003-10-09 | — | — | WO | disclosed |