Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP8 | P22894 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.43 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7093633 | 0.94 | MMP8 (0.52) | MMP8MEN1NPC1KMT2ASMN1; SMN2 | |
| SCHEMBL6908528 | 0.89 | MMP8 (0.64) | MMP8MEN1NPC1KMT2ASMN1; SMN2 | |
| SCHEMBL7090828 | 0.88 | L3MBTL1 (0.52) | MMP8NPC1KMT2ASMN1; SMN2CA12 | |
| SCHEMBL7092555 | 0.88 | MMP8 (0.59) | MMP8MEN1NPC1KMT2ASMN1; SMN2 | |
| SCHEMBL28579101 | 0.87 | MMP8 (0.55) | MMP8MEN1NPC1KMT2ASMN1; SMN2 | |
| SCHEMBL3796213 | 0.82 | CA12 (0.48) | MEN1KMT2ASMN1; SMN2CA12CA1 | |
| SCHEMBL8200333 | 0.82 | MMP8 (0.55) | MMP8MEN1NPC1KMT2ASMN1; SMN2 | |
| SCHEMBL7090567 | 0.82 | MMP8 (0.52) | MMP8MEN1NPC1KMT2ASMN1; SMN2 | |
| SCHEMBL3798068 | 0.82 | CA12 (0.53) | MMP8MEN1NPC1KMT2ACA12 | |
| SCHEMBL1041533 | 0.81 | MMP8 (0.51) | MMP8MEN1NPC1KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003084935-A2 | DIARYL PYRIMIDINONE DERIVATIVES USEFUL FOR THE TREATMENT OF INFLAMMATION AND IMMUNOGOLICAL DISEASES | ORCHID CHEMICALS & PHARMACEUTICALS LTD (IN) | 2003-10-16 | — | — | WO | disclosed |