Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP8 | P22894 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 4/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.51 |
| ▸ | NPC1 | O15118 | 2/20 | 0.51 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | CES2 | O00748 | 1/20 | 0.42 |
| ▸ | CES1 | P23141 | 1/20 | 0.42 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 3/20 | 0.41 |
| ▸ | CA1 | P00915 | 3/20 | 0.41 |
| ▸ | CA2 | P00918 | 3/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7094136 | 0.94 | MMP8 (0.56) | MMP8MEN1KMT2ANPC1CYP19A1 | |
| SCHEMBL6908528 | 0.89 | MMP8 (0.64) | MMP8MEN1KMT2ANPC1ALDH1A1 | |
| SCHEMBL7090828 | 0.88 | L3MBTL1 (0.52) | MMP8KMT2ANPC1SMN1; SMN2CES2 | |
| SCHEMBL8200333 | 0.88 | MMP8 (0.55) | MMP8MEN1KMT2ANPC1ALDH1A1 | |
| SCHEMBL1041533 | 0.84 | MMP8 (0.51) | MMP8MEN1KMT2ANPC1ALDH1A1 | |
| SCHEMBL28579101 | 0.84 | MMP8 (0.55) | MMP8MEN1KMT2ANPC1SMN1; SMN2 | |
| SCHEMBL7093345 | 0.84 | NPC1 (0.56) | MMP8MEN1KMT2ANPC1CYP19A1 | |
| SCHEMBL7095774 | 0.83 | MMP8 (0.50) | MMP8MEN1KMT2ANPC1ALDH1A1 | |
| SCHEMBL27324944 | 0.83 | MMP8 (0.50) | MMP8MEN1KMT2ANPC1ALDH1A1 | |
| SCHEMBL4064086 | 0.83 | MMP8 (0.51) | MMP8MEN1KMT2ANPC1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003084935-A2 | DIARYL PYRIMIDINONE DERIVATIVES USEFUL FOR THE TREATMENT OF INFLAMMATION AND IMMUNOGOLICAL DISEASES | ORCHID CHEMICALS & PHARMACEUTICALS LTD (IN) | 2003-10-16 | — | — | WO | disclosed |