Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 2/20 | 0.60 |
| ▸ | DRD3 | P35462 | 1/20 | 0.60 |
| ▸ | HTR2C | P28335 | 1/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.58 |
| ▸ | GAA | P10253 | 2/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.56 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.56 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.56 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.55 |
| ▸ | NPC1 | O15118 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.54 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.54 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.54 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.54 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.54 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.54 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.54 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL75255 | 0.85 | DRD2 (0.64) | DRD2DRD3HTR2CKDM4EALDH1A1 | |
| SCHEMBL30595731 | 0.85 | DRD2 (0.64) | DRD2DRD3HTR2CKDM4EALDH1A1 | |
| SCHEMBL3246963 | 0.82 | KDM4E (0.68) | DRD2DRD3HTR2CKDM4EALDH1A1 | |
| SCHEMBL7097103 | 0.81 | KDM4E (0.65) | KDM4EALDH1A1HSD17B10NPC1RAB9A | |
| SCHEMBL7087439 | 0.81 | DRD2 (0.63) | DRD2DRD3HTR2CKDM4EALDH1A1 | |
| SCHEMBL5349216 | 0.80 | DRD2 (0.68) | DRD2DRD3HTR2CKDM4EALDH1A1 | |
| SCHEMBL9397179 | 0.80 | DRD2 (0.74) | DRD2DRD3HTR2CKDM4EALDH1A1 | |
| SCHEMBL7098599 | 0.80 | RAB9A (0.65) | KDM4ENPC1RAB9AHDAC3HDAC4 | |
| SCHEMBL10064737 | 0.79 | HRH4 (0.49) | KDM4EALDH1A1NPC1RAB9ALMNA | |
| SCHEMBL13101463 | 0.78 | DRD2 (0.63) | DRD2DRD3HTR2CKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1200439-B1 | 1,2-DIHYDRO-1-OXO-PARAZINO(1,2-A) INDOLE DERIVATIVES | NOVUSPHARMA SPA (IT) | 2003-06-25 | — | — | EP | disclosed |