Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.59 |
| ▸ | TP53 | P04637 | 4/20 | 0.59 |
| ▸ | TSHR | P16473 | 3/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.59 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.59 |
| ▸ | MAOB | P27338 | 8/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.51 |
| ▸ | MAOA | P21397 | 4/20 | 0.51 |
| ▸ | NPC1 | O15118 | 2/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | PPARG | P37231 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7979964 | 1.00 | ALDH1A1 (0.59) | ALDH1A1TP53TSHRCYP3A4HIF1A | |
| SCHEMBL5515785 | 1.00 | ALDH1A1 (0.59) | ALDH1A1TP53TSHRCYP3A4HIF1A | |
| SCHEMBL8151638 | 0.83 | ALDH1A1 (0.62) | ALDH1A1TP53TSHRCYP3A4HIF1A | |
| SCHEMBL983383 | 0.81 | MAOB (0.57) | ALDH1A1TP53CYP3A4SMN1; SMN2MAOB | |
| SCHEMBL6782574 | 0.79 | MAOB (0.65) | ALDH1A1SMN1; SMN2MAOBMAOANPC1 | |
| SCHEMBL985688 | 0.79 | MAOB (0.54) | ALDH1A1TP53CYP3A4MAOBTDP1 | |
| SCHEMBL107322 | 0.78 | MAOB (0.83) | ALDH1A1TSHRCYP3A4MAOBTDP1 | |
| SCHEMBL1715242 | 0.78 | ALDH1A1 (0.71) | ALDH1A1TP53TSHRCYP3A4HIF1A | |
| SCHEMBL21094081 | 0.78 | TDP1 (0.79) | ALDH1A1TP53TSHRCYP3A4HIF1A | |
| SCHEMBL20677146 | 0.78 | TDP1 (0.79) | ALDH1A1TP53TSHRCYP3A4HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11773086-B2 | Fungal modulators | TRUSTEES OF BOSTON UNIVERSITY (US) | 2023-10-03 | — | — | US | disclosed |
| US-11773086-B2 | Fungal modulators | TRUSTEES OF BOSTON UNIVERSITY (US) | 2023-10-03 | — | — | US | disclosed |
| US-20220064152-A1 | NOVEL FUNGAL MODULATORS | TRUSTEES OF BOSTON UNIVERSITY (US) | 2022-03-03 | — | — | US | disclosed |
| US-6605618-B2 | Antidiabetic agents; hypoglycemic agents; anticholesterol agents; side effect reduction | WYETH | 2003-08-12 | — | — | US | disclosed |
| US-20030018045-A1 | Heterocyclic beta-3 adrenergic receptor agonists | WYETH (US) | 2003-01-23 | — | — | US | disclosed |
| US-6458817-B1 | AROMATIC SUBSTITUTED SUFURE OR SULFOXIDE OR SULFONE DERIVATIVES CONTAINING SECONDAY AMINE AND HYDROXY GROUPS ARE USEFUL IN TREATNG METABOLIC DISORDERS MEDIATED BY INSULIN RESISTANCE OR HYPERGLYCEMIA IN MAMMALS | WYETH | 2002-10-01 | — | — | US | disclosed |
| US-6451814-B1 | SUBSTITUTED 4-((4-AMINO-5-HYDROXYPHENYL)-OXY-)PIPERIDINE ANALOGS; METABOLIC DISORDERS; ANTIDIABETIC AGENTS; ATHERO-SCLEROSIS, GASTROINTESTINAL DISORDERS, GLAUCOMA, NEUROGENETIC INFLAMMATION, OCULAR HYPERTENSION AND FREQUENT URINATION | WYETH | 2002-09-17 | — | — | US | disclosed |
| US-20020040023-A1 | Substituted arylsulfides, arylsulfoxides and arylsulfones as beta-3 adrenergic receptor agonists | AMERICAN HOME PRODUCTS CORPORATION (US) | 2002-04-04 | — | — | US | disclosed |
| US-20020028832-A1 | Heterocyclic beta-3 adrenergic receptor agonists | AMERICAN HOME PRODUCTS CORPORATION (US) | 2002-03-07 | — | — | US | disclosed |
| WO-2001017993-A1 | ALKYLPIPERIDI NYLBENZO [D] ISOXAZOLE DERIVATIVES HAVING PSYCHOTROPIC ACTIVITY, PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME, AND A PROCESS FOR THE PREPARATION OF THE ACTIVE INGREDIENT | EGIS Gyógyszergyár Rt. (HU) | 2001-03-15 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030018045-A1 | Heterocyclic beta-3 adrenergic receptor agonists | ADRB2, ADRB1, ADRB3 | ALDH1A1 725/4885TP53 4790/4885TSHR 603/4885 |
| US-11773086-B2 | Fungal modulators | ABCB11, ABCB1, ABCC1 | ALDH1A1 3436/4885TP53 1316/4885TSHR 4863/4885 |
| US-20020040023-A1 | Substituted arylsulfides, arylsulfoxides and arylsulfones as beta-3 adrenergic receptor agonists | ADRB1, ADRB3, GPR119 | ALDH1A1 602/4885TP53 4670/4885TSHR 296/4885 |
| US-20020028832-A1 | Heterocyclic beta-3 adrenergic receptor agonists | ADRB1, ADRB3, ADRB2 | ALDH1A1 524/4885TP53 4644/4885TSHR 552/4885 |
| US-20220064152-A1 | NOVEL FUNGAL MODULATORS | ABCB11, ABCB1, ABCC1 | ALDH1A1 3676/4885TP53 1931/4885TSHR 4863/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.