SCHEMBL7095099

SCHEMBL7095099

CCc1cc(-c2ccccc2)ccc1OC(C)=O

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CFD P00746 1/20 0.54
TDP1 Q9NUW8 2/20 0.51
MAPT P10636 2/20 0.51
GAA P10253 2/20 0.51
LMNA P02545 1/20 0.51
MAOB P27338 1/20 0.49
BACE1 P56817 3/20 0.48
HPGD P15428 2/20 0.46
ALOX5 P09917 1/20 0.46
AKT1 P31749 1/20 0.46
SRD5A2 P31213 1/20 0.45
KDM4E B2RXH2 2/20 0.45
ALDH1A1 P00352 2/20 0.45
TSHR P16473 2/20 0.45
HSD17B10 Q99714 2/20 0.45
ESR1 P03372 1/20 0.45
ITGB3 P05106 1/20 0.45
ITGA2B P08514 1/20 0.45
HMGB1 P09429 1/20 0.45
GGT1 P19440 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7095256 0.89 CFD (0.50) CFDTDP1MAPTGAALMNA
SCHEMBL27318392 0.83 CFD (0.61) CFDTDP1MAPTGAALMNA
SCHEMBL14700513 0.80 CFD (0.46) CFDBACE1ALOX5AKT1ALDH1A1
SCHEMBL10429619 0.80 BACE1 (0.61) CFDTDP1MAPTGAALMNA
SCHEMBL27604736 0.79 BACE1 (0.50) CFDTDP1MAPTGAALMNA
Benzene SCHEMBL28173619 0.79 PTGS2 (0.58) TDP1MAPTGAALMNAHPGD
SCHEMBL10723672 0.79 CFD (0.87) CFDTDP1MAPTGAALMNA
SCHEMBL3784778 0.79 CFD (0.56) CFDTDP1MAPTGAALMNA
SCHEMBL9293387 0.79 CFD (0.60) CFDTDP1MAPTGAALMNA
SCHEMBL27702813 0.79 CFD (0.56) CFDTDP1MAPTGAALMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1205195-C Disubstituted biphexyloxazolines BAYER AG (DE) 2005-06-08 CN disclosed
EP-0970059-B1 DISUBSTITUTED BIPHENYLOXAZOLINES BAYER CROPSCIENCE AG (DE) 2003-08-20 EP disclosed
US-20020086892-A1 For controlling animal pests, in particular: insects, arachnids and nematodes BAYER AKTIENGESELLSCHAFT (DE) 2002-07-04 US disclosed
US-6410581-B1 INSECTICIDES, MITICIDES, NEMATOCIDES BAYER AKTIENGESELLSCHAFT (DE) 2002-06-25 US disclosed
CN-1255127-A Disubstituted biphexyloxazolines BAYER AG (DE) 2000-05-31 CN disclosed
EP-0970059-A1 DISUBSTITUTED BIPHENYLOXAZOLINES BAYER AG (DE) 2000-01-12 EP disclosed
WO-1998039310-A1 DISUBSTITUTED BIPHENYLOXAZOLINES BAYER AKTIENGESELLSCHAFT (DE) 1998-09-11 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020086892-A1 For controlling animal pests, in particular: insects, arachnids and nematodes ATXN2, HAX1, ANTXR2 CFD 2643/4885TDP1 2429/4885MAPT 4396/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.