SCHEMBL7095256

SCHEMBL7095256

CCCc1cc(-c2ccccc2)ccc1OC(C)=O

nearest known ligand 0.54

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
CFD P00746 1/20 0.50
MAPT P10636 1/20 0.48
TDP1 Q9NUW8 1/20 0.48
LMNA P02545 1/20 0.48
GAA P10253 1/20 0.48
MAOB P27338 1/20 0.46
BACE1 P56817 3/20 0.45
HPGD P15428 1/20 0.43
ALOX5 P09917 1/20 0.43
PPARG P37231 3/20 0.43
PPARA Q07869 2/20 0.43
AKT1 P31749 1/20 0.43
FPR1 P21462 3/20 0.43
PTGS2 P35354 1/20 0.42
PPARD Q03181 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7095099 0.89 CFD (0.54) CFDMAPTTDP1LMNAGAA
SCHEMBL7578265 0.85 ALOX5 (0.48) ALOX5PPARGPPARAPPARD
SCHEMBL28898703 0.80 KDM4E (0.51) MAPTLMNAGAABACE1ALOX5
SCHEMBL27318392 0.79 CFD (0.61) CFDMAPTTDP1LMNAGAA
SCHEMBL4032384 0.79 PTGS2 (0.54) TDP1HPGDPPARGPPARAFPR1
SCHEMBL9165101 0.79 TSHR (0.63) CFDLMNAGAAPPARGPPARA
SCHEMBL6696944 0.78 LMNA (0.47) CFDLMNAGAAPPARGPPARA
SCHEMBL27427403 0.78 PPARG (0.43) MAPTTDP1GAAHPGDALOX5
SCHEMBL27510448 0.77 HSD17B1 (0.59) MAPTHPGD
SCHEMBL10429619 0.76 BACE1 (0.61) CFDMAPTTDP1LMNAGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0970059-B1 DISUBSTITUTED BIPHENYLOXAZOLINES BAYER CROPSCIENCE AG (DE) 2003-08-20 EP disclosed
US-20020086892-A1 For controlling animal pests, in particular: insects, arachnids and nematodes BAYER AKTIENGESELLSCHAFT (DE) 2002-07-04 US disclosed
US-6410581-B1 INSECTICIDES, MITICIDES, NEMATOCIDES BAYER AKTIENGESELLSCHAFT (DE) 2002-06-25 US disclosed
EP-0970059-A1 DISUBSTITUTED BIPHENYLOXAZOLINES BAYER AG (DE) 2000-01-12 EP disclosed
WO-1998039310-A1 DISUBSTITUTED BIPHENYLOXAZOLINES BAYER AKTIENGESELLSCHAFT (DE) 1998-09-11 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020086892-A1 For controlling animal pests, in particular: insects, arachnids and nematodes ATXN2, HAX1, ANTXR2 CFD 2643/4885MAPT 4396/4885TDP1 2429/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.