Known targets — ChEMBL curated mechanism
AGTR1DHFRGABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTNR3C2PBP2XPTGS1PTGS2VKORC1blablaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAftsImrcAmrcBmrdApbp1apbp1bpbp2apbp2bpbp3polthyA
The experimentally established mechanism targets of Potassium Ion. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 2/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.32 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7102090 | 0.97 | CA1 (0.44) | CA1TP53CA2NFKB1GPR84 | |
| SCHEMBL8411826 | 0.93 | CA2 (0.38) | CA1TP53CA2NFKB1 | |
| Potassium Ion SCHEMBL7098116 | 0.84 | CA2 (0.40) | CA1TP53CA2 | |
| SCHEMBL7100586 | 0.81 | CA2 (0.43) | CA1TP53CA2 | |
| SCHEMBL7102069 | 0.78 | — | — | |
| Ammonia Solution, Strong SCHEMBL7100042 | 0.77 | TP53 (0.38) | CA1TP53GPR84 | |
| Ammonia Solution, Strong SCHEMBL7100043 | 0.77 | TP53 (0.38) | CA1TP53GPR84 | |
| SCHEMBL7095228 | 0.77 | TP53 (0.38) | CA1TP53GPR84 | |
| SCHEMBL7102093 | 0.77 | TP53 (0.38) | CA1TP53GPR84 | |
| Potassium Ion SCHEMBL7100634 | 0.73 | CA2 (0.37) | CA1TP53CA2NFKB1GPR84 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0964036-B1 | Water-based ball-point pen ink composition | PILOT INK CO LTD (JP) | 2003-08-27 | — | — | EP | disclosed |
| US-6261352-B1 | BETAINE, SULFO ESTER | THE PILOT INK CO., LTD. (JP) | 2001-07-17 | — | — | US | disclosed |
| EP-0964036-A2 | Water-based ball-point pen ink composition | THE PILOT INK CO., LTD. (JP) | 1999-12-15 | — | — | EP | disclosed |