Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.41 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.40 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.39 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7094471 | 0.80 | ALOX5 (0.39) | MEN1KMT2AKDM4EALDH1A1GAA | |
| SCHEMBL7096822 | 0.74 | HTT (0.45) | MEN1KMT2AKDM4EALDH1A1GAA | |
| SCHEMBL9015990 | 0.73 | HTT (0.44) | MEN1KMT2AKDM4EALDH1A1GAA | |
| SCHEMBL9053303 | 0.73 | HTT (0.44) | MEN1KMT2AKDM4EALDH1A1GAA | |
| SCHEMBL8005768 | 0.73 | MEN1 (0.52) | MEN1KMT2AKDM4EALDH1A1GAA | |
| SCHEMBL688109 | 0.72 | THRA (0.46) | MEN1KMT2AALDH1A1POLBALOX5 | |
| SCHEMBL9015951 | 0.71 | MEN1 (0.55) | MEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL2910532 | 0.70 | POLB (0.62) | KMT2AKDM4EALDH1A1GAATP53 | |
| SCHEMBL1495906 | 0.70 | CREBBP (0.55) | MEN1KMT2AKDM4EALDH1A1GAA | |
| SCHEMBL8669046 | 0.70 | HTR1A (0.64) | MEN1KMT2ATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1361875-A2 | NOVEL HETEROCYCLIC AMIDE DERIVATIVES AND THEIR USE AS DOPAMINE D3 RECEPTOR LIGANDS | Aventis Pharmaceuticals Inc. (US) | 2003-11-19 | — | — | EP | claimed |
| WO-2002066469-A2 | NOVEL HETEROCYCLIC AMIDE DERIVATIVES AND THEIR USE AS DOPAMINE D3 RECEPTOR LIGANDS | AVENTIS PHARMACEUTICALS INC. (US) | 2002-08-29 | — | — | WO | claimed |
| EP-0901469-B1 | ARYLALKYLPIPERAZINE COMPOUNDS AS ANTIOXIDANTS | UNIV MONASH (AU) | 2003-08-27 | — | — | EP | disclosed |
| US-6232314-B1 | SUCH AS 1-(2-(4-CHLOROPHENYL)-2-HYDROXY)ETHYL-4-(3,5-BIS(1,1-DIMETHYLETHYL)-4 -HYDROXYPHENYL)METHYLPIPERAZINE; USED TO TREAT STROKE, CARDIAC ARREST, ISCHAEMIA, HYPOXIA, HYPOGLYCAEMIA, EPILEPSY, AND AMYOTROPHIC LATERAL SCLEROSIS | MONASH UNIVERSITY (AU) | 2001-05-15 | — | — | US | disclosed |