Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | PSMB5 | P28074 | 2/20 | 0.49 |
| ▸ | PSMB1 | P20618 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2851306 | 0.83 | ALDH1A1 (0.55) | KDM4ETSHRPOLBL3MBTL1ALDH1A1 | |
| SCHEMBL19500099 | 0.81 | PSMB5 (0.52) | SMN1; SMN2TSHRPSMB5PSMB1POLB | |
| SCHEMBL28254025 | 0.81 | KDM4E (0.50) | KDM4ESMN1; SMN2TSHRPSMB5PSMB1 | |
| SCHEMBL9523478 | 0.81 | KDM4E (0.47) | KDM4ESMN1; SMN2TSHRGAAPOLB | |
| SCHEMBL11964126 | 0.79 | TSHR (0.54) | KDM4ESMN1; SMN2TSHRPSMB5PSMB1 | |
| SCHEMBL19509381 | 0.79 | PSMB5 (0.50) | SMN1; SMN2TSHRPSMB5PSMB1POLB | |
| SCHEMBL9752669 | 0.79 | TSHR (0.57) | SMN1; SMN2TSHRPSMB5PSMB1POLB | |
| SCHEMBL21190075 | 0.78 | GAA (0.51) | TSHRGAAPOLBL3MBTL1 | |
| SCHEMBL1280773 | 0.77 | TSHR (0.56) | KDM4ETSHRPSMB5PSMB1POLB | |
| SCHEMBL21334490 | 0.77 | LMNA (0.49) | KDM4ESMN1; SMN2TSHRPSMB1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116082237-B | Nitrogen-containing heterocyclic compound and preparation method thereof | 安徽中医药大学 | 2025-04-22 | — | — | CN | claimed |
| US-20210177851-A1 | NOVEL BENZYLAMINO SUBSTITUTED QUINAZOLINES AND DERIVATIVES AS SOS1 INHIBITORS | BOEHRINGER INGELHEIM INT (DE) | 2021-06-17 | — | — | US | disclosed |
| EP-2861577-B1 | TERTIARY AMINES, MEDICAMENTS CONTAINING SAID AMINES, USE THEREOF AND PROCESSES FOR THE PREPARATION THEREOF | BOEHRINGER INGELHEIM INT (DE) | 2017-01-04 | — | — | EP | disclosed |
| US-8921243-B2 | Fabrics comprising a photocatalyst to produce singlet oxygen from ambient oxygen | VENTANA RESEARCH CORPORATION | 2014-12-30 | — | — | US | disclosed |
| US-8921243-B2 | Fabrics comprising a photocatalyst to produce singlet oxygen from ambient oxygen | VENTANA RESEARCH CORPORATION | 2014-12-30 | — | — | US | disclosed |
| US-8481446-B2 | Chemically-resistant coating composition | VENTANA RESEARCH CORPORATION | 2013-07-09 | — | — | US | disclosed |
| US-8481446-B2 | Chemically-resistant coating composition | VENTANA RESEARCH CORPORATION | 2013-07-09 | — | — | US | disclosed |
| US-20120135651-A1 | Fabrics Comprising a Photocatalyst to Produce Singlet Oxygen from Ambient Oxygen | VENTANA RESEARCH CORPORATION | 2012-05-31 | — | — | US | disclosed |
| US-20120135651-A1 | Fabrics Comprising a Photocatalyst to Produce Singlet Oxygen from Ambient Oxygen | VENTANA RESEARCH CORPORATION | 2012-05-31 | — | — | US | disclosed |
| WO-2011142838-A2 | CHEMICALLY-RESISTANT COATING COMPOSITION | LOMBARID JOHN L (US) | 2011-11-17 | — | — | WO | disclosed |
| US-20100279850-A1 | CHEMICALLY-RESISTANT COATING COMPOSITION | VENTANA RESEARCH CORPORATION | 2010-11-04 | — | — | US | disclosed |
| US-20100279850-A1 | CHEMICALLY-RESISTANT COATING COMPOSITION | VENTANA RESEARCH CORPORATION | 2010-11-04 | — | — | US | disclosed |
| WO-2010118180-A1 | FABRICS COMPRISING A PHOTOCATALYST TO PRODUCE SINGLET OXYGEN FROM AMBIENT OXYGEN | LOMBARDI JOHN L (US) | 2010-10-14 | — | — | WO | disclosed |
| EP-0815084-B1 | LACTAM-CONTAINING HYDROXAMIC ACID DERIVATIVES, THEIR PREPARATION AND THEIR USE AS INHIBITORS OF MATRIX METALLOPROTEASE | PROCTER & GAMBLE (US) | 2003-08-27 | — | — | EP | disclosed |
| EP-0489458-B1 | Hydroxyquinolone derivatives | MERCK SHARP & DOHME (GB) | 1995-06-07 | — | — | EP | disclosed |
| US-5252584-A | Antagonist for treating nervous system disorders | MERCK SHARP & DOHME LIMITED (GB) | 1993-10-12 | — | — | US | disclosed |
| EP-0489458-A1 | Hydroxyquinolone derivatives | MERCK SHARP & DOHME LTD. (GB) | 1992-06-10 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100279850-A1 | CHEMICALLY-RESISTANT COATING COMPOSITION | DNMT1, VCL, DNMT3L | KDM4E 173/4885SMN1; SMN2 992/4885TSHR 4873/4885 |
| US-20210177851-A1 | NOVEL BENZYLAMINO SUBSTITUTED QUINAZOLINES AND DERIVATIVES AS SOS1 INHIBITORS | SOS1, SOS2, SOST | KDM4E 3689/4885SMN1; SMN2 1069/4885TSHR 2962/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.