Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY5R | Q15761 | 4/20 | 0.45 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.41 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.41 |
| ▸ | KDR | P35968 | 1/20 | 0.41 |
| ▸ | MAPKAPK2 | P49137 | 3/20 | 0.39 |
| ▸ | PDE4A | P27815 | 1/20 | 0.39 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | RIPK1 | Q13546 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5945897 | 0.76 | ERN1 (0.49) | KDRPDE4ASMN1; SMN2KDM4EL3MBTL1 | |
| SCHEMBL7009747 | 0.76 | CCNB2 (0.63) | RIPK1CDK1CCNB2CCNB1GSK3A | |
| SCHEMBL7101502 | 0.76 | CCNB2 (0.44) | NPY5RPDE4ASMN1; SMN2KDM4EL3MBTL1 | |
| SCHEMBL7100815 | 0.75 | RIPK1 (0.42) | NPY5RPDE4ASMN1; SMN2KDM4EL3MBTL1 | |
| SCHEMBL6285594 | 0.74 | GAA (0.41) | PDGFRBFGFR1KDRPDE4AKDM4E | |
| SCHEMBL7101268 | 0.73 | RIPK1 (0.43) | NPY5RSMN1; SMN2KDM4EL3MBTL1LMNA | |
| SCHEMBL7014990 | 0.73 | RIPK1 (0.48) | NPY5RSMN1; SMN2KDM4EL3MBTL1LMNA | |
| SCHEMBL7016833 | 0.73 | CCNB2 (0.42) | NPY5RPDE4ASMN1; SMN2KDM4EL3MBTL1 | |
| SCHEMBL7017680 | 0.73 | RIPK1 (0.43) | NPY5RPDE10ASMN1; SMN2KDM4EL3MBTL1 | |
| SCHEMBL6286952 | 0.69 | NPY5R (0.39) | NPY5RPDGFRBFGFR1KDRPDE4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1294718-A2 | 6,5-FUSED BICYCLIC HETEROCYCLES | WARNER-LAMBERT COMPANY LLC (US) | 2003-03-26 | — | — | EP | claimed |
| WO-2001096336-A2 | 6,5-FUSED BICYCLIC HETEROCYCLES | WARNER-LAMBERT COMPANY (US) | 2001-12-20 | — | — | WO | claimed |