Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.40 |
| ▸ | TP53 | P04637 | 4/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 5/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.39 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CDC42BPA | Q5VT25 | 1/20 | 0.39 |
| ▸ | HTR1D | P28221 | 2/20 | 0.38 |
| ▸ | HTR1B | P28222 | 2/20 | 0.38 |
| ▸ | HTR2A | P28223 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7098174 | 0.87 | LMNA (0.42) | MAPTTP53POLBLMNASMN1; SMN2 | |
| SCHEMBL7072131 | 0.87 | LTB4R2 (0.43) | MAPTTP53POLBLMNAALDH1A1 | |
| SCHEMBL7084908 | 0.86 | ABHD6 (0.39) | TP53LMNASMN1; SMN2HTTCYP2C9 | |
| SCHEMBL7097848 | 0.86 | MAPT (0.41) | MAPTTP53POLBLMNASMN1; SMN2 | |
| SCHEMBL7097252 | 0.85 | MAPT (0.45) | MAPTTP53POLBLMNASMN1; SMN2 | |
| SCHEMBL7098737 | 0.84 | LMNA (0.40) | MAPTTP53POLBLMNASMN1; SMN2 | |
| SCHEMBL7098768 | 0.77 | ALDH1A1 (0.46) | POLBALDH1A1 | |
| SCHEMBL7084912 | 0.75 | TP53 (0.39) | MAPTTP53SMN1; SMN2ALDH1A1HPGD | |
| SCHEMBL7094641 | 0.74 | F10 (0.39) | — | |
| SCHEMBL7087198 | 0.74 | RAB9A (0.42) | MAPTTP53POLBLMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030171579-A1 | Urethane derivatives | MERCK PATENT GMBH (DE) | 2003-09-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030171579-A1 | Urethane derivatives | UTS2R, PLAUR, IL1A | MAPT 4210/4885TP53 4080/4885POLB 1006/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.