Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGAM | O43451 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | SI | P14410 | 1/20 | 0.46 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 5/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.40 |
| ▸ | TET2 | Q6N021 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | CA12 | O43570 | 2/20 | 0.32 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.32 |
| ▸ | CA2 | P00918 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | POLA1 | P09884 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18130134 | 0.85 | MGAM (0.46) | MGAMGAASIMGAM2TSHR | |
| SCHEMBL197340 | 0.82 | MGAM (0.48) | MGAMGAASIMGAM2TSHR | |
| SCHEMBL23009489 | 0.81 | FAAH (0.35) | HSD17B10KMT2AMEN1CA2ALDH1A1 | |
| SCHEMBL6248725 | 0.79 | GAA (0.58) | MGAMGAASIMGAM2TSHR | |
| SCHEMBL7101659 | 0.79 | MGAM (0.41) | MGAMGAASIMGAM2TSHR | |
| SCHEMBL204758 | 0.79 | GAA (0.50) | MGAMGAASIMGAM2TSHR | |
| SCHEMBL129536 | 0.78 | MGAM (0.44) | MGAMGAASIMGAM2TSHR | |
| SCHEMBL1407070 | 0.78 | MGAM (0.44) | MGAMGAASIMGAM2TSHR | |
| SCHEMBL7100983 | 0.78 | LMNA (0.38) | TSHRKMT2AMEN1LMNAALDH1A1 | |
| SCHEMBL20690118 | 0.78 | MGAM (0.39) | MGAMGAASIMGAM2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230382856-A1 | METHOD OF PRODUCING 3-METHYL-4-HALO-INDOLE DERIVATIVE | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2023-11-30 | — | — | US | disclosed |
| EP-4238961-A1 | METHOD OF PRODUCING 3-METHYL-4-HALO-INDOLE DERIVATIVE | Daiichi Sankyo Company, Limited (JP) | 2023-09-06 | — | — | EP | disclosed |
| CN-116368125-A | Process for producing 3-methyl-4-halogeno-indole derivative | 第一三共株式会社 | 2023-06-30 | — | — | CN | disclosed |
| EP-1038861-B1 | 4-FLUORO-3-OXOCARBOXYLIC ESTERS AND PROCESS FOR PRODUCING THE SAME | UBE INDUSTRIES (JP) | 2003-09-03 | — | — | EP | disclosed |
| US-6593488-B1 | Reacting 2-fluorocarboxylate with carboxylate | UBE INDUSTRIES, LTD. (JP) | 2003-07-15 | — | — | US | disclosed |
| EP-1038861-A1 | 4-FLUORO-3-OXOCARBOXYLIC ESTERS AND PROCESS FOR PRODUCING THE SAME | UBE INDUSTRIES LIMITED (JP) | 2000-09-27 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230382856-A1 | METHOD OF PRODUCING 3-METHYL-4-HALO-INDOLE DERIVATIVE | INMT, TDO2, HNMT | MGAM 1097/4885GAA 3549/4885SI 843/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.