Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BAZ2B | Q9UIF8 | 4/20 | 0.46 |
| ▸ | BAZ2A | Q9UIF9 | 4/20 | 0.46 |
| ▸ | BRD9 | Q9H8M2 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | GFER | P55789 | 1/20 | 0.45 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.44 |
| ▸ | ALPL | P05186 | 1/20 | 0.44 |
| ▸ | ALPI | P09923 | 1/20 | 0.44 |
| ▸ | ALPG | P10696 | 1/20 | 0.44 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.41 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.39 |
| ▸ | BCL2 | P10415 | 2/20 | 0.39 |
| ▸ | MAOA | P21397 | 2/20 | 0.38 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.38 |
| ▸ | ESR1 | P03372 | 1/20 | 0.38 |
| ▸ | UGT1A1 | P22309 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2862404 | 0.86 | MCL1 (0.54) | GAAPOLBGFERMCL1ALPL | |
| SCHEMBL6801877 | 0.77 | PTGS2 (0.49) | BAZ2BBAZ2ABRD9ESR2ENPP2 | |
| SCHEMBL18618313 | 0.76 | HSD11B1 (0.48) | BAZ2BBAZ2ABRD9GAALMNA | |
| SCHEMBL29588550 | 0.76 | HSD11B1 (0.48) | BAZ2BBAZ2ABRD9GAALMNA | |
| SCHEMBL3275593 | 0.75 | PTGS1 (0.61) | GAAPOLBGFERMCL1ALPL | |
| SCHEMBL4636219 | 0.75 | ESR2 (0.55) | GAAPOLBGFERTDP1L3MBTL1 | |
| SCHEMBL6820364 | 0.74 | CA2 (0.50) | BAZ2BBAZ2ABRD9HSD11B1ALDH1A1 | |
| SCHEMBL27866825 | 0.72 | ALOX5AP (0.54) | — | |
| SCHEMBL6512541 | 0.72 | PTPRC (0.46) | BAZ2BBAZ2ABRD9DNMT1HSD11B1 | |
| SCHEMBL1163819 | 0.72 | HPGD (0.49) | GAAMCL1ESR2ESR1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1267809-A1 | HAIR COLOURING AND CONDITIONING COMPOSITIONS | THE PROCTER & GAMBLE COMPANY (US) | 2003-01-02 | — | — | EP | disclosed |
| WO-2001076545-A1 | HAIR COLOURING AND CONDITIONING COMPOSITIONS | THE PROCTER & GAMBLE COMPANY (US) | 2001-10-18 | — | — | WO | disclosed |