Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IGF1R | P08069 | 1/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | PNMT | P11086 | 1/20 | 0.47 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.47 |
| ▸ | SIGMAR1 | Q99720 | 13/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.47 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.47 |
| ▸ | CEL | P19835 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2652238 | 0.89 | PNMT (0.50) | PNMTTAAR1SIGMAR1ALDH1A1MAPT | |
| SCHEMBL11401683 | 0.85 | PRMT5 (0.58) | IGF1RALOX15PNMTTAAR1SIGMAR1 | |
| Ammonia Solution, Strong SCHEMBL6194671 | 0.80 | PNMT (0.52) | IGF1RALOX15PNMTTAAR1SIGMAR1 | |
| SCHEMBL27629025 | 0.80 | CEL (0.47) | IGF1RALOX15TAAR1SIGMAR1ALDH1A1 | |
| SCHEMBL21788431 | 0.77 | POLB (0.49) | PNMTTAAR1SIGMAR1SMN1; SMN2SLC6A2 | |
| SCHEMBL25787111 | 0.77 | POLB (0.49) | PNMTTAAR1SIGMAR1SMN1; SMN2SLC6A2 | |
| SCHEMBL6854749 | 0.76 | SIGMAR1 (0.56) | SIGMAR1ALDH1A1MAPTSMN1; SMN2OPRK1 | |
| SCHEMBL20382689 | 0.74 | CEL (0.48) | IGF1RALOX15SIGMAR1SLC6A2SLC6A4 | |
| SCHEMBL21413972 | 0.73 | SIGMAR1 (0.51) | SIGMAR1CYP1A2CYP2D6 | |
| SCHEMBL9133788 | 0.72 | CEL (0.50) | IGF1RALOX15SIGMAR1SLC6A2SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003095441-A1 | INHIBITORS OF HEPATITIS C VIRUS RNA-DEPENDENT RNA POLYMERASE, AND COMPOSITIONS AND TREATMENTS USING THE SAME | PFIZER INC. (US) | 2003-11-20 | — | — | WO | disclosed |