Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRD1 | P41143 | 1/20 | 0.46 |
| ▸ | IDH1 | O75874 | 2/20 | 0.46 |
| ▸ | DRD2 | P14416 | 7/20 | 0.44 |
| ▸ | DRD3 | P35462 | 5/20 | 0.44 |
| ▸ | DRD4 | P21917 | 3/20 | 0.44 |
| ▸ | HTR2A | P28223 | 2/20 | 0.44 |
| ▸ | HTR7 | P34969 | 2/20 | 0.44 |
| ▸ | ADRA1A | P35348 | 3/20 | 0.42 |
| ▸ | ADRA1B | P35368 | 3/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.42 |
| ▸ | ACHE | P22303 | 3/20 | 0.41 |
| ▸ | HTR1A | P08908 | 2/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.41 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.41 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.41 |
| ▸ | BACE1 | P56817 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7775567 | 0.87 | OPRD1 (0.49) | OPRD1IDH1DRD2DRD3DRD4 | |
| SCHEMBL7773713 | 0.86 | DRD2 (0.52) | OPRD1IDH1DRD2DRD3DRD4 | |
| SCHEMBL7775644 | 0.86 | P2RX7 (0.45) | DRD2DRD3DRD4P2RX7 | |
| SCHEMBL7098292 | 0.81 | DRD2 (0.42) | OPRD1IDH1DRD2DRD3DRD4 | |
| Hydrochloric Acid SCHEMBL7775564 | 0.80 | IDH1 (0.45) | OPRD1IDH1DRD2DRD3DRD4 | |
| Hydrochloric Acid SCHEMBL7775562 | 0.80 | IDH1 (0.44) | OPRD1IDH1DRD2DRD3DRD4 | |
| SCHEMBL9255788 | 0.77 | ACHE (0.52) | OPRD1IDH1DRD2DRD3DRD4 | |
| SCHEMBL27342830 | 0.77 | ACHE (0.52) | OPRD1IDH1DRD2DRD3DRD4 | |
| SCHEMBL7097673 | 0.77 | DRD3 (0.60) | DRD2DRD3DRD4HTR2AHTR7 | |
| SCHEMBL7097689 | 0.77 | DRD3 (0.60) | DRD2DRD3DRD4HTR2AHTR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0690051-B1 | DIAZACYCLOALKANEALKYLSULFONAMIDE DERIVATIVE | AZWELL INC (JP) | 2001-07-18 | — | — | EP | disclosed |
| EP-0690051-A1 | DIAZACYCLOALKANEALKYLSULFONAMIDE DERIVATIVE | NIPPON SHOJI KABUSHIKI KAISHA (JP) | 1996-01-03 | — | — | EP | disclosed |