Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.60 |
| ▸ | MAPT | P10636 | 2/20 | 0.60 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.59 |
| ▸ | GAA | P10253 | 2/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | AKT1 | P31749 | 2/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | G6PD | P11413 | 1/20 | 0.49 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.48 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7018385 | 0.84 | TP53 (0.46) | MEN1KMT2AALDH1A1POLBRAB9A | |
| SCHEMBL7016812 | 0.84 | TP53 (0.46) | MEN1KMT2AALDH1A1POLBRAB9A | |
| SCHEMBL14571460 | 0.81 | KMT2A (0.80) | MEN1KMT2AMAPTHSP90AA1ALDH1A1 | |
| SCHEMBL7103501 | 0.81 | ALDH1A1 (0.61) | MEN1KMT2AMAPTHSP90AA1ALDH1A1 | |
| SCHEMBL7014520 | 0.81 | ALDH1A1 (0.52) | MEN1KMT2AMAPTALDH1A1RAB9A | |
| SCHEMBL7020798 | 0.81 | KCNH2 (0.50) | TP53KCNH2HRH3 | |
| SCHEMBL7017597 | 0.81 | CXCR3 (0.44) | ALDH1A1TP53 | |
| SCHEMBL31277320 | 0.80 | KMT2A (0.70) | MEN1KMT2AMAPTHSP90AA1ALDH1A1 | |
| SCHEMBL7023261 | 0.80 | ALDH1A1 (0.70) | MEN1KMT2AMAPTALDH1A1RAB9A | |
| SCHEMBL7011889 | 0.80 | ALDH1A1 (0.63) | KMT2AMAPTALDH1A1RAB9ANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003106435-A1 | FUSED-RING PYRIMIDIN-4(3H)-ONE DERIVATIVES, PROCESSES FOR THE PREPARATION AND USES THEREOF | SANKYO COMPANY, LIMITED (JP) | 2003-12-24 | — | — | WO | disclosed |