Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 1/20 | 0.50 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.50 |
| ▸ | MLYCD | O95822 | 7/20 | 0.49 |
| ▸ | CXCR3 | P49682 | 7/20 | 0.48 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | ESR1 | P03372 | 1/20 | 0.45 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7017597 | 0.88 | CXCR3 (0.44) | MLYCDCXCR3TP53 | |
| SCHEMBL7016853 | 0.85 | MLYCD (0.43) | MLYCDCXCR3TP53 | |
| SCHEMBL7100648 | 0.83 | CXCR3 (0.44) | MLYCDCXCR3 | |
| SCHEMBL6979418 | 0.82 | KCNH2 (0.59) | KCNH2HRH3TRPV1ESR1ESR2 | |
| SCHEMBL7016812 | 0.82 | TP53 (0.46) | TP53 | |
| SCHEMBL7018385 | 0.82 | TP53 (0.46) | TP53 | |
| SCHEMBL7100250 | 0.81 | MEN1 (0.60) | KCNH2HRH3TP53 | |
| SCHEMBL7021106 | 0.80 | ALDH1A1 (0.57) | CXCR3 | |
| SCHEMBL7104431 | 0.80 | ALDH1A1 (0.50) | TP53 | |
| SCHEMBL7014520 | 0.79 | ALDH1A1 (0.52) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003106435-A1 | FUSED-RING PYRIMIDIN-4(3H)-ONE DERIVATIVES, PROCESSES FOR THE PREPARATION AND USES THEREOF | SANKYO COMPANY, LIMITED (JP) | 2003-12-24 | — | — | WO | disclosed |