Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | TOP2A | P11388 | 2/20 | 0.42 |
| ▸ | CHRM4 | P08173 | 3/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.41 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | MMP8 | P22894 | 1/20 | 0.40 |
| ▸ | GPR88 | Q9GZN0 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7101016 | 0.91 | NPC1 (0.48) | LMNAALDH1A1SMN1; SMN2KMT2ANPC1 | |
| SCHEMBL7100498 | 0.88 | MMP8 (0.49) | LMNAALDH1A1SMN1; SMN2GAAKMT2A | |
| SCHEMBL7099669 | 0.82 | KMT2A (0.47) | ALDH1A1KMT2AHPGD | |
| SCHEMBL7101691 | 0.82 | ALDH1A1 (0.46) | LMNAALDH1A1SMN1; SMN2KMT2ARAB9A | |
| SCHEMBL7100973 | 0.78 | TSHR (0.51) | LMNAALDH1A1SMN1; SMN2GAAKMT2A | |
| SCHEMBL7101644 | 0.76 | LMNA (0.46) | LMNAALDH1A1SMN1; SMN2GAACHRM4 | |
| SCHEMBL28759435 | 0.76 | LMNA (0.53) | LMNAALDH1A1SMN1; SMN2GAACHRM4 | |
| SCHEMBL23869396 | 0.75 | ALDH1A1 (0.49) | LMNAALDH1A1KMT2A | |
| SCHEMBL28924679 | 0.75 | CES2 (0.41) | LMNAALDH1A1GAATOP2ACHRM1 | |
| SCHEMBL7100929 | 0.73 | MGAM (0.38) | LMNAALDH1A1GAACHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1038861-B1 | 4-FLUORO-3-OXOCARBOXYLIC ESTERS AND PROCESS FOR PRODUCING THE SAME | UBE INDUSTRIES (JP) | 2003-09-03 | — | — | EP | disclosed |
| US-6593488-B1 | Reacting 2-fluorocarboxylate with carboxylate | UBE INDUSTRIES, LTD. (JP) | 2003-07-15 | — | — | US | disclosed |
| EP-1038861-A1 | 4-FLUORO-3-OXOCARBOXYLIC ESTERS AND PROCESS FOR PRODUCING THE SAME | UBE INDUSTRIES LIMITED (JP) | 2000-09-27 | — | — | EP | disclosed |