Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.48 |
| ▸ | RAB9A | P51151 | 3/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 3/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | GPR88 | Q9GZN0 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | FAAH | O00519 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7101663 | 0.91 | LMNA (0.46) | NPC1RAB9ASMN1; SMN2LMNAKMT2A | |
| SCHEMBL7100498 | 0.85 | MMP8 (0.49) | SMN1; SMN2LMNATSHRMEN1KMT2A | |
| SCHEMBL28003749 | 0.83 | TSHR (0.53) | NPC1RAB9ASMN1; SMN2LMNATSHR | |
| SCHEMBL7099669 | 0.80 | KMT2A (0.47) | TSHRL3MBTL1POLBMEN1KMT2A | |
| SCHEMBL7101691 | 0.79 | ALDH1A1 (0.46) | RAB9ASMN1; SMN2LMNATSHRKMT2A | |
| SCHEMBL23191566 | 0.77 | TSHR (0.53) | NPC1RAB9ASMN1; SMN2LMNATSHR | |
| SCHEMBL7101022 | 0.77 | TSHR (0.46) | NPC1RAB9ASMN1; SMN2LMNATSHR | |
| SCHEMBL27723973 | 0.77 | NPSR1 (0.49) | SMN1; SMN2TDP1POLBMEN1KMT2A | |
| SCHEMBL17057059 | 0.76 | FAAH (0.47) | SMN1; SMN2TSHRMAPK1ALDH1A1FAAH | |
| SCHEMBL9467365 | 0.76 | ALDH1A1 (0.54) | NPC1RAB9ASMN1; SMN2LMNATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1038861-B1 | 4-FLUORO-3-OXOCARBOXYLIC ESTERS AND PROCESS FOR PRODUCING THE SAME | UBE INDUSTRIES (JP) | 2003-09-03 | — | — | EP | disclosed |
| US-6593488-B1 | Reacting 2-fluorocarboxylate with carboxylate | UBE INDUSTRIES, LTD. (JP) | 2003-07-15 | — | — | US | disclosed |
| EP-1038861-A1 | 4-FLUORO-3-OXOCARBOXYLIC ESTERS AND PROCESS FOR PRODUCING THE SAME | UBE INDUSTRIES LIMITED (JP) | 2000-09-27 | — | — | EP | disclosed |