Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 3/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | APEX1 | P27695 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | RECQL | P46063 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.43 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7100665 | 0.86 | ALDH1A1 (0.63) | ALDH1A1LMNAALOX15APEX1MAPK1 | |
| SCHEMBL3813557 | 0.85 | ACHE (0.56) | ACHEALDH1A1LMNAALOX15APEX1 | |
| SCHEMBL5217775 | 0.82 | GSK3B (0.56) | ALDH1A1LMNAMEN1KMT2ASLC2A1 | |
| SCHEMBL2290396 | 0.76 | ALDH1A1 (0.60) | ALDH1A1MAPTMEN1KMT2ANPC1 | |
| SCHEMBL24260590 | 0.74 | ALDH1A1 (0.57) | ALDH1A1LMNAALOX15APEX1MAPK1 | |
| SCHEMBL14435692 | 0.74 | LDHA (0.50) | ALDH1A1LMNATDP1MEN1KMT2A | |
| SCHEMBL20225318 | 0.73 | ALDH1A1 (0.56) | ALDH1A1LMNAALOX15APEX1MAPK1 | |
| SCHEMBL7162385 | 0.72 | MAPT (0.60) | ALDH1A1LMNAALOX15APEX1MAPK1 | |
| SCHEMBL23295612 | 0.72 | HDAC3 (0.50) | ALDH1A1MAPK1TDP1EPHX2L3MBTL1 | |
| SCHEMBL4853025 | 0.72 | ALDH1A1 (0.55) | ALDH1A1LMNAALOX15APEX1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0114607-B1 | DIBENZOYL METHANE DERIVATIVES, PROCESS FOR THEIR PRODUCTION AND THEIR USE | HAARMANN & REIMER GMBH (DE) | 1985-09-04 | — | — | EP | disclosed |