SCHEMBL710134

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL711773	0.90	HDAC6 (0.42)	ALDH1A1HDAC1HDAC8HDAC6TSHR
	SCHEMBL712003	0.89	HPGD (0.47)	ALDH1A1HPGDCYP1A2CYP2C9CYP2C19
	SCHEMBL711275	0.88	HDAC6 (0.41)	ALDH1A1HPGDSMN1; SMN2HDAC1HDAC8
	SCHEMBL711999	0.84	HDAC1 (0.46)	ALDH1A1HPGDCYP1A2SMN1; SMN2HDAC1
	SCHEMBL709376	0.81	SCN9A (0.43)	ALDH1A1HPGDCYP2C19SMN1; SMN2LMNA
	SCHEMBL12011295	0.78	HDAC6 (0.39)	ALDH1A1HDAC1HDAC8HDAC6TSHR
	SCHEMBL714409	0.76	HDAC6 (0.43)	SMN1; SMN2HDAC1HDAC8HDAC6ACLY
	SCHEMBL8697590	0.74	SMN1; SMN2 (0.48)	ALDH1A1HPGDCYP1A2CYP2C9CYP2C19
	SCHEMBL27871304	0.72	ALDH1A1 (0.49)	ALDH1A1HPGDSMN1; SMN2HDAC1HDAC8
	SCHEMBL8697588	0.72	CYP1A2 (0.45)	ALDH1A1HPGDCYP1A2CYP2C9CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.