SCHEMBL712003

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL710134	0.89	ALDH1A1 (0.47)	HPGDALDH1A1KDM4ERAB9ANPC1
	SCHEMBL711773	0.86	HDAC6 (0.42)	ALDH1A1ERBB2LMNATSHR
	SCHEMBL711275	0.84	HDAC6 (0.41)	HPGDALDH1A1SMN1; SMN2MAPTMAPK1
	SCHEMBL711999	0.80	HDAC1 (0.46)	HPGDALDH1A1KDM4ERAB9ANPC1
	SCHEMBL12011295	0.75	HDAC6 (0.39)	ALDH1A1MAPTLMNATSHR
	SCHEMBL714409	0.73	HDAC6 (0.43)	KDM4ESMN1; SMN2LMNA
	SCHEMBL709376	0.71	SCN9A (0.43)	HPGDALDH1A1SMN1; SMN2MAPTLMNA
	SCHEMBL10415979	0.70	SMN1; SMN2 (0.66)	HPGDALDH1A1L3MBTL1KDM4ERAB9A
	SCHEMBL3080870	0.69	CLPP (0.50)	HPGDALDH1A1RAB9ASMN1; SMN2MAPT
	SCHEMBL12846670	0.69	ESR1 (0.47)	HPGDALDH1A1L3MBTL1KDM4ESMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.