Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.41 |
| ▸ | ACLY | P53396 | 3/20 | 0.39 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.37 |
| ▸ | WDR5 | P61964 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | ANO1 | Q5XXA6 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL711773 | 0.91 | HDAC6 (0.42) | HDAC6HDAC1HDAC8ACLYMAPK14 | |
| SCHEMBL710134 | 0.88 | ALDH1A1 (0.47) | HDAC6HDAC1HDAC8ACLYMAPT | |
| SCHEMBL711999 | 0.85 | HDAC1 (0.46) | HDAC6HDAC1HDAC8ACLYMAPT | |
| SCHEMBL712003 | 0.84 | HPGD (0.47) | MAPTHPGDLMNAALDH1A1TSHR | |
| SCHEMBL12011295 | 0.79 | HDAC6 (0.39) | HDAC6HDAC1HDAC8ACLYMAPK14 | |
| SCHEMBL714409 | 0.77 | HDAC6 (0.43) | HDAC6HDAC1HDAC8ACLYWDR5 | |
| SCHEMBL27871304 | 0.73 | ALDH1A1 (0.49) | HDAC6HDAC1HDAC8HPGDLMNA | |
| SCHEMBL3080870 | 0.73 | CLPP (0.50) | WDR5MAPTHPGDLMNAALDH1A1 | |
| SCHEMBL712255 | 0.70 | SCN9A (0.45) | — | |
| SCHEMBL709376 | 0.68 | SCN9A (0.43) | MAPTHPGDLMNAALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8252925-B2 | Method for the production of 3-phenyl(thio)uracils and dithiouracils | BASF AKTIENGESELLSCHAFT (DE) | 2012-08-28 | — | — | US | disclosed |
| US-8252925-B2 | Method for the production of 3-phenyl(thio)uracils and dithiouracils | BASF AKTIENGESELLSCHAFT (DE) | 2012-08-28 | — | — | US | disclosed |
| US-8124818-B2 | Method for the production of 3-phenyl(thio) uracils and dithiouracils | BASF AKTIENGESELLSCHAFT (DE) | 2012-02-28 | — | — | US | disclosed |
| US-8124818-B2 | Method for the production of 3-phenyl(thio) uracils and dithiouracils | BASF AKTIENGESELLSCHAFT (DE) | 2012-02-28 | — | — | US | disclosed |
| US-20110152522-A1 | METHOD FOR THE PRODUCTION OF 3-PHENYL(THIO) URACILS AND DITHIOURACILS | BASF AKTIENGESSELSCHAFT (DE) | 2011-06-23 | — | — | US | disclosed |
| US-20110152522-A1 | METHOD FOR THE PRODUCTION OF 3-PHENYL(THIO) URACILS AND DITHIOURACILS | BASF AKTIENGESSELSCHAFT (DE) | 2011-06-23 | — | — | US | disclosed |
| US-20080033174-A1 | Method for the Production of 3-Phenyl (Thio) Uracils and Dithiouracils | BASF AKTIENGESELLSCHAFT (DE) | 2008-02-07 | — | — | US | disclosed |
| US-20080033174-A1 | Method for the Production of 3-Phenyl (Thio) Uracils and Dithiouracils | BASF AKTIENGESELLSCHAFT (DE) | 2008-02-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080033174-A1 | Method for the Production of 3-Phenyl (Thio) Uracils and Dithiouracils | TPMT, TYMP, TYMS | HDAC6 2437/4885HDAC1 2627/4885HDAC8 4101/4885 |
| US-20110152522-A1 | METHOD FOR THE PRODUCTION OF 3-PHENYL(THIO) URACILS AND DITHIOURACILS | TPMT, TYMP, TYMS | HDAC6 2437/4885HDAC1 2627/4885HDAC8 4101/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.