SCHEMBL7101461

SCHEMBL7101461

COc1ccc(CC#N)c(C#N)c1C#N

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 0.41
LMNA P02545 1/20 0.41
CYP2C9 P11712 1/20 0.41
NPC1 O15118 1/20 0.39
RAB9A P51151 1/20 0.39
GAA P10253 1/20 0.37
ALDH1A1 P00352 5/20 0.37
KDM4E B2RXH2 2/20 0.37
IMPDH2 P12268 1/20 0.37
IMPDH1 P20839 1/20 0.37
USP2 O75604 1/20 0.37
MAPK1 P28482 2/20 0.35
HTT P42858 1/20 0.35
PRKCZ Q05513 1/20 0.35
L3MBTL1 Q9Y468 1/20 0.35
HPGD P15428 1/20 0.35
KMT2A Q03164 2/20 0.34
MEN1 O00255 1/20 0.34
PKM P14618 1/20 0.34
FDPS P14324 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31124656 0.82 MAPT (0.53) MAPTLMNACYP2C9NPC1RAB9A
SCHEMBL7064467 0.82 MAPT (0.53) MAPTLMNACYP2C9NPC1RAB9A
SCHEMBL20343311 0.76 ALOX5 (0.46) MAPTLMNACYP2C9ARHSD17B10
SCHEMBL954640 0.76 MEN1 (0.47) MAPTLMNAALDH1A1KDM4EKMT2A
SCHEMBL6234576 0.76 AOC3 (0.49) MAPTLMNAGAAALDH1A1KDM4E
SCHEMBL7097601 0.74 TUBB1 (0.35) MAPTALDH1A1KDM4EIMPDH2IMPDH1
SCHEMBL7625688 0.74 POLB (0.36) MAPTLMNANPC1RAB9AALDH1A1
SCHEMBL9786028 0.73 AOC3 (0.39) MAPTLMNAALDH1A1KDM4EMAPK1
SCHEMBL27758118 0.73 SLC6A4 (0.49) MAPTGAAALDH1A1KDM4EUSP2
SCHEMBL25764548 0.73 LMNA (0.44) MAPTLMNACYP2C9NPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6528657-B2 For use in electroluminescence light emission element and can emit lights of various colors when an energy such as electric energy or electromagnetic energy is applied thereto TAIHO INDUSTRIES CO., LTD. (JP) 2003-03-04 US disclosed
US-20030023099-A1 Novel fluorescent carbazole derivative HIROSE ENGINEERING CO., LTD. (JP) 2003-01-30 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030023099-A1 Novel fluorescent carbazole derivative CBR3, AANAT, SIRT3 MAPT 1479/4885LMNA 4453/4885CYP2C9 1110/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.