SCHEMBL7064467

SCHEMBL7064467

COc1ccc(OC)c(C#N)c1C#N

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 0.53
LMNA P02545 1/20 0.53
CYP2C9 P11712 1/20 0.53
ALDH1A1 P00352 3/20 0.48
KDM4E B2RXH2 2/20 0.48
IMPDH2 P12268 1/20 0.48
IMPDH1 P20839 1/20 0.48
USP2 O75604 1/20 0.48
GAA P10253 1/20 0.46
RAB9A P51151 3/20 0.44
NPC1 O15118 2/20 0.44
HTT P42858 1/20 0.43
PRKCZ Q05513 1/20 0.43
MAPK1 P28482 1/20 0.43
L3MBTL1 Q9Y468 1/20 0.43
KMT2A Q03164 2/20 0.42
CA12 O43570 1/20 0.41
CA1 P00915 1/20 0.41
CA2 P00918 1/20 0.41
CA4 P22748 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31124656 1.00 MAPT (0.53) MAPTLMNACYP2C9ALDH1A1KDM4E
SCHEMBL26259630 0.87 MAPT (0.48) MAPTLMNACYP2C9ALDH1A1KDM4E
SCHEMBL24514955 0.87 LMNA (0.44) MAPTLMNACYP2C9ALDH1A1KDM4E
Sulfuric Acid Dimethyl Ester SCHEMBL8521270 0.85 MAPT (0.47) MAPTLMNACYP2C9ALDH1A1KDM4E
SCHEMBL4739158 0.84 RAB9A (0.59) MAPTLMNACYP2C9ALDH1A1KDM4E
SCHEMBL7101461 0.82 MAPT (0.41) MAPTLMNACYP2C9ALDH1A1KDM4E
SCHEMBL15389432 0.80 ALDH1A1 (0.52) MAPTLMNACYP2C9ALDH1A1KDM4E
SCHEMBL12957782 0.80 ALDH1A1 (0.52) MAPTLMNACYP2C9ALDH1A1KDM4E
SCHEMBL186647 0.80 MAPT (0.43) MAPTLMNACYP2C9ALDH1A1KDM4E
SCHEMBL5277144 0.79 LMNA (0.42) MAPTLMNACYP2C9ALDH1A1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240339644-A1 Symmetric Redox Molecules Using Synergistic Electron Directing Pairs ExxonMobil Technology and Engineering Company (US) 2024-10-10 US disclosed
US-20140170073-A1 NANOPARTICULATE PROBE FOR IN VIVO MONITORING OF TISSUE OXYGENATION THE OHIO STATE UNIVERSITY RESEARCH FOUNDATION (US) 2014-06-19 US disclosed
US-8066973-B2 Nanoparticulate probe for in vivo monitoring of tissue oxygenation THE OHIO STATE UNIVERSITY RESEARCH FOUNDATION (US) 2011-11-29 US disclosed
EP-1092721-B1 Chiral glucosides and their use as chiral dopants for the production of cholesteric liquid crystalline compositions BASF AG (DE) 2007-12-19 EP disclosed
US-20070041909-A1 Nanoparticulate probe for in vivo monitoring of tissue oxygenation THE OHIO STATE UNIVERSITY RESEARCH FOUNDATION (US) 2007-02-22 US disclosed
EP-0960185-B1 PHOTOBLEACHING COMPOSITIONS EFFECTIVE ON DINGY FABRIC UNIV CASE WESTERN RESERVE (US) 2003-05-28 EP disclosed
EP-0851898-B1 LOW HUE PHOTOBLEACHES PROCTER & GAMBLE (US) 2001-10-04 EP disclosed
US-6262005-B1 PHTHALOCYANINE AND NAPHTHALOCYANINES COMPRISING AXIAL MOIETIES SELECTED FOR THEIR HYDROPHOBIC CHARACTER AS MEASURED BY THEIR CLOGP. THE PROCTER & GAMBLE COMPANY 2001-07-17 US disclosed
US-5916481-A ORGANOSILICONE PHTHALOCYANINE COMPOUNDS FOR BLEACHES THE PROCTER & GAMBLE COMPANY (US) 1999-06-29 US disclosed
CN-1197470-A Low hue photobleaches PROCTER & GAMBLE (US) 1998-10-28 CN disclosed
US-5679661-A ORGANOSILICON PHTHALOCYANINE AND NAPHTHALOCYANINES, USEFUL FOR TREATING DISPOSABLE ARTICLE OF PAPER AND TEXTILE, SEWAGE AND SWIMMING POOLS TREATMENT THE PROCTER & GAMBLE COMPANY (US) 1997-10-21 US disclosed
WO-1997005202-A1 LOW HUE PHOTOBLEACHES THE PROCTER & GAMBLE COMPANY (US) 1997-02-13 WO disclosed
WO-1997005203-A1 LOW HUE PHOTODISINFECTANTS THE PROCTER & GAMBLE COMPANY (US) 1997-02-13 WO disclosed
US-5480873-A ARTHRITIS LILLY INDUSTRIES LIMITED (GB) 1996-01-02 US disclosed
CN-1079732-A Medical compounds LILLY INDUSTRIES LTD (GB) 1993-12-22 CN disclosed
EP-0570091-A1 Anthraquinone derivatives, process for their preparation and their use as medicaments LILLY INDUSTRIES LIMITED (GB) 1993-11-18 EP disclosed
US-4122261-A Polycyclic iminoisoindoline chelates STERLING DRUG INC. (US) 1978-10-24 US disclosed
US-4066653-A 1-IMINO-3-(4-IMINO-5-THIAZOLIDINYLIDENE)ISOINDOLINES STERLING DRUG INC. (US) 1978-01-03 US disclosed
US-4032656-A ANTIPROSTAGLANDIN ACTIVITY, ANTIDIARRHEA AGENTS SMITHKLINE CORPORATION (US) 1977-06-28 US disclosed
US-3993658-A Thiazolidinylidene-isoindolines STERLING DRUG INC. (US) 1976-11-23 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070041909-A1 Nanoparticulate probe for in vivo monitoring of tissue oxygenation LPO, TNNC1, PPOX MAPT 1225/4885LMNA 863/4885CYP2C9 1485/4885
US-20140170073-A1 NANOPARTICULATE PROBE FOR IN VIVO MONITORING OF TISSUE OXYGENATION LPO, TNNC1, PPOX MAPT 1346/4885LMNA 780/4885CYP2C9 1497/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.