Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | ADORA2A | P29274 | 10/20 | 0.39 |
| ▸ | ADORA1 | P30542 | 6/20 | 0.38 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2041342 | 0.82 | PKM (0.42) | PKMMEN1KMT2AHTTHIF1A | |
| Hydrochloric Acid SCHEMBL27680690 | 0.81 | PKM (0.41) | PKMMEN1KMT2AHTTHIF1A | |
| SCHEMBL27521615 | 0.80 | ALDH1A1 (0.40) | PKMMEN1KMT2AHTTHIF1A | |
| SCHEMBL6624655 | 0.79 | L3MBTL1 (0.41) | PKMMEN1KMT2AHTTHIF1A | |
| SCHEMBL1219078 | 0.77 | PKM (0.38) | PKMMEN1KMT2AHTTHIF1A | |
| SCHEMBL11688470 | 0.77 | PKM (0.38) | PKMMEN1KMT2AHTTHIF1A | |
| SCHEMBL4755861 | 0.77 | ALDH1A1 (0.38) | PKMMEN1KMT2AHTTHIF1A | |
| SCHEMBL27846260 | 0.75 | PKM (0.51) | PKMMEN1KMT2AHTTHIF1A | |
| SCHEMBL2155976 | 0.75 | PKM (0.36) | PKMMEN1KMT2AHTTHIF1A | |
| SCHEMBL28111989 | 0.75 | LMNA (0.36) | PKMMEN1KMT2AHTTHIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1289983-A2 | HETEROARYLALKANOIC ACIDS AS INTEGRIN RECEPTOR ANTAGONISTS | Pharmacia Corporation (US) | 2003-03-12 | — | — | EP | disclosed |
| WO-2001096334-A2 | HETEROARYLALKANOIC ACIDS AS INTEGRIN RECEPTOR ANTAGONISTS | PHARMACIA CORPORATION (US) | 2001-12-20 | — | — | WO | disclosed |