Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.32 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.32 |
| ▸ | RELA | Q04206 | 1/20 | 0.32 |
| ▸ | ELANE | P08246 | 1/20 | 0.32 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.31 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.31 |
| ▸ | PREP | P48147 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17079962 | 0.90 | NFKB1 (0.30) | NFKB1NFKB2RELAELANE | |
| SCHEMBL29919514 | 0.90 | NFKB1 (0.30) | NFKB1NFKB2RELAELANE | |
| SCHEMBL17190445 | 0.89 | CHRM2 (0.33) | CHRM2CHRM1CHRM3PREP | |
| SCHEMBL18449644 | 0.88 | ATM (0.33) | — | |
| SCHEMBL17190443 | 0.88 | — | — | |
| SCHEMBL17190382 | 0.87 | GAA (0.33) | — | |
| SCHEMBL17192596 | 0.86 | MAPT (0.33) | MAPT | |
| SCHEMBL17190448 | 0.86 | — | — | |
| SCHEMBL17190452 | 0.85 | — | — | |
| SCHEMBL17190431 | 0.84 | USP2 (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3240413-B1 | PICOLINAMIDE COMPOUNDS WITH FUNGICIDAL ACTIVITY | DOW AGROSCIENCES LLC (US) | 2020-05-13 | — | — | EP | disclosed |
| US-10450282-B2 | Stereospecific process for 3-heterocyclylcycloaliphatic-1,2-diols | ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI (US) | 2019-10-22 | — | — | US | disclosed |
| US-10433555-B2 | Picolinamide compounds with fungicidal activity | DOW AGROSCIENCES LLC (US) | 2019-10-08 | — | — | US | disclosed |
| EP-3331867-A1 | STEREOSPECIFIC PROCESS FOR 3-HETEROCYCLYLCYCLOALIPHATIC-1,2-DIOLS | Icahn School of Medicine at Mount Sinai (US) | 2018-06-13 | — | — | EP | disclosed |
| US-20180000085-A1 | USE OF PICOLINAMIDE COMPOUNDS WITH FUNGICIDAL ACTIVITY | CORTEVA AGRISCIENCE LLC | 2018-01-04 | — | — | US | disclosed |
| EP-3240412-A1 | USE OF PICOLINAMIDE COMPOUNDS WITH FUNGICIDAL ACTIVITY | Dow Agrosciences LLC (US) | 2017-11-08 | — | — | EP | disclosed |
| EP-3240413-A1 | PICOLINAMIDE COMPOUNDS WITH FUNGICIDAL ACTIVITY | Dow Agrosciences LLC (US) | 2017-11-08 | — | — | EP | disclosed |
| WO-2017024229-A1 | STEREOSPECIFIC PROCESS FOR 3-HETEROCYCLYLCYCLOALIPHATIC-1,2-DIOLS | ICAHN SCHOOL OF MEDECINE AT MOUNT SINAI (US) | 2017-02-09 | — | — | WO | disclosed |
| EP-2847185-B1 | MACROCYCLIC PICOLINAMIDES AS FUNGICIDES | DOW AGROSCIENCES LLC (US) | 2016-11-16 | — | — | EP | disclosed |
| US-9439422-B2 | Use of macrocyclic picolinamides as fungicides | DOW AGROSCIENCES LLC (US) | 2016-09-13 | — | — | US | disclosed |
| US-20150094340-A1 | USE OF MACROCYCLIC PICOLINAMIDES AS FUNGICIDES | DOW AGROSCIENCES LLC | 2015-04-02 | — | — | US | disclosed |
| EP-2847185-A2 | MACROCYCLIC PICOLINAMIDES AS FUNGICIDES | Dow AgroSciences LLC (US) | 2015-03-18 | — | — | EP | disclosed |
| US-20140275171-A1 | MACROCYCLIC PICOLINAMIDES AS FUNGICIDES | DOW AGROSCIENCES LLC | 2014-09-18 | — | — | US | disclosed |
| US-8785479-B2 | Macrocyclic picolinamides as fungicides | DOW AGROSCIENCES, LLC. (US) | 2014-07-22 | — | — | US | disclosed |
| WO-2013169662-A2 | MACROCYCLIC PICOLINAMIDES AS FUNGICIDES | DOW AGROSCIENCES LLC (US) | 2013-11-14 | — | — | WO | disclosed |
| US-20130296375-A1 | MACROCYCLIC PICOLINAMIDES AS FUNGICIDES | DOW AGROSCIENCES LLC (US) | 2013-11-07 | — | — | US | disclosed |
| EP-0977742-B1 | THE PREPARATION OF ENANTIOMERICALLY ENRICHED OXAZOLONES AND ALPHA, ALPHA-DISUBSTITUTED AMINO ACIDS | UNIV LELAND STANFORD JUNIOR (US) | 2003-09-10 | — | — | EP | disclosed |
| US-6130337-A | ALKYLATING AN ALLYLIC ELECTROPHILE WITH A 5-OXAZOLONE IN PRESENCE OF A BASE | BOARD OF TRUSTEES OF LELAND STANFORD JUNIOR UNIVERSITY (US) | 2000-10-10 | — | — | US | disclosed |
| EP-0977742-A1 | THE PREPARATION OF ENANTIOMERICALLY ENRICHED OXAZOLONES AND ALPHA, ALPHA-DISUBSTITUTED AMINO ACIDS | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 2000-02-09 | — | — | EP | disclosed |
| WO-1998046578-A1 | THE PREPARATION OF ENANTIOMERICALLY ENRICHED OXAZOLONES AND α,α-DISUBSTITUTED AMINO ACIDS | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 1998-10-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140275171-A1 | MACROCYCLIC PICOLINAMIDES AS FUNGICIDES | FKBP14, FKBP2, CYP51A1 | MAPT 1429/4885NFKB1 4587/4885NFKB2 4726/4885 |
| US-10433555-B2 | Picolinamide compounds with fungicidal activity | PFAS, CASP2, CYP1A2 | MAPT 1306/4885NFKB1 4243/4885NFKB2 4204/4885 |
| US-20130296375-A1 | MACROCYCLIC PICOLINAMIDES AS FUNGICIDES | FKBP14, FKBP2, CYP51A1 | MAPT 1429/4885NFKB1 4587/4885NFKB2 4726/4885 |
| US-10450282-B2 | Stereospecific process for 3-heterocyclylcycloaliphatic-1,2-diols | DDT, ODC1, CBR1 | MAPT 4855/4885NFKB1 3716/4885NFKB2 3309/4885 |
| US-20150094340-A1 | USE OF MACROCYCLIC PICOLINAMIDES AS FUNGICIDES | FKBP14, CYP4F12, CYP1A2 | MAPT 1945/4885NFKB1 4649/4885NFKB2 4769/4885 |
| US-20180000085-A1 | USE OF PICOLINAMIDE COMPOUNDS WITH FUNGICIDAL ACTIVITY | PFAS, CYP1A2, CYP51A1 | MAPT 1987/4885NFKB1 4387/4885NFKB2 4484/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.