Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.37 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.36 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 2/20 | 0.34 |
| ▸ | ADRA1D | P25100 | 3/20 | 0.34 |
| ▸ | ADRA1A | P35348 | 3/20 | 0.34 |
| ▸ | ADRA1B | P35368 | 3/20 | 0.34 |
| ▸ | SLC6A7 | Q99884 | 2/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | HTR7 | P34969 | 1/20 | 0.33 |
| ▸ | HTR6 | P50406 | 1/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.33 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.33 |
| ▸ | ALPL | P05186 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8073886 | 0.91 | GBA1 (0.35) | KDM2BADRA1DADRA1AADRA1BKMT2A | |
| SCHEMBL7771962 | 0.71 | CA1 (0.39) | ADRA1DADRA1AADRA1BSLC6A3 | |
| SCHEMBL7775649 | 0.71 | CA1 (0.38) | ADRA1DADRA1AADRA1BSLC6A3 | |
| SCHEMBL7105280 | 0.65 | CHIT1 (0.34) | — | |
| SCHEMBL7104982 | 0.62 | HTR7 (0.51) | HTR1ADRD2HTR2AHTR7HTR6 | |
| SCHEMBL14900454 | 0.58 | GRM2 (0.45) | TAAR1GRM2MAOBSLC6A7MCHR1 | |
| SCHEMBL2690730 | 0.57 | TAAR1 (1.00) | TAAR1MAOB | |
| SCHEMBL7104976 | 0.57 | CACNA2D1 (0.53) | ADRA1ASLC6A3HTR1ADRD2HTR2A | |
| SCHEMBL22639146 | 0.57 | GRM2 (0.41) | TAAR1GRM2MAOBSLC6A7SLC6A3 | |
| SCHEMBL4695679 | 0.57 | SLC6A7 (0.57) | TAAR1GRM2MAOBSLC6A7SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1020443-B1 | PROCESS FOR PRODUCING PIPERAZINESULFONAMIDE DERIVATIVES AND SALTS THEREOF | AZWELL INC (JP) | 2003-09-10 | — | — | EP | disclosed |
| EP-1020443-A1 | PROCESS FOR PRODUCING PIPERAZINESULFONAMIDE DERIVATIVES AND SALTS THEREOF | Azwell Inc. (JP) | 2000-07-19 | — | — | EP | disclosed |