SCHEMBL7103290

SCHEMBL7103290

[N-]=[N+]=C1C=Cc2c(cccc2S(=O)(=O)O)C1=O.[NaH]

nearest known ligand 0.33

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
TTR P02766 1/20 0.33
PGAM1 P18669 1/20 0.32
PTPRC P08575 1/20 0.31
STAT3 P40763 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8608275 0.98 TTR (0.33) TTRPGAM1PTPRCSTAT3
SCHEMBL823887 0.98 TTR (0.33) TTRPGAM1PTPRCSTAT3
Hydrochloric Acid SCHEMBL7749007 0.97 TTR (0.33) TTRPGAM1PTPRCSTAT3
SCHEMBL10769121 0.86 ALPL (0.35) PGAM1
SCHEMBL7645795 0.84
Hydrochloric Acid SCHEMBL8976635 0.84 TTR (0.32) TTR
SCHEMBL9644548 0.83 STAT3 (0.41) STAT3
SCHEMBL823909 0.83
SCHEMBL818753 0.83 BRD9 (0.31) PTPRC
SCHEMBL7103287 0.82 PKLR (0.36) PGAM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0965580-B1 Method for producing 1,2-Naphthoquinone-2-diazide derivative TOYO GOSEI KOGYO KK (JP) 2003-09-03 EP disclosed
US-6077941-A Method for producing 1,2-naphthoquinone-2-diazide derivatives TOYO GOSEI KOGYO CO., LTD. (JP) 2000-06-20 US disclosed
EP-0965580-A1 Method for producing 1,2-Naphthoquinone-2-diazide derivative Toyo Gosei Kogyo Co., Ltd. (JP) 1999-12-22 EP disclosed
US-4125650-A Resist image hardening process INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 1978-11-14 US disclosed