Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.43 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7109274 | 0.93 | CNR1 (0.50) | CNR1KDM4ENPC1RAB9ASCN2A | |
| SCHEMBL7108474 | 0.89 | CNR1 (0.53) | CNR1KDM4ENPC1RAB9AHPGD | |
| SCHEMBL10674362 | 0.80 | KDM4E (0.67) | KDM4ENPC1RAB9ALMNAHPGD | |
| SCHEMBL7109193 | 0.79 | ICAM1 (0.40) | KDM4EHPGDSMN1; SMN2 | |
| SCHEMBL18130913 | 0.79 | SIRT6 (0.52) | CNR1NPC1RAB9AHPGDMAOB | |
| SCHEMBL7104658 | 0.78 | SMN1; SMN2 (0.35) | CNR1KDM4ERAB9ASCN2ASCN10A | |
| SCHEMBL23015757 | 0.77 | CNR1 (0.45) | CNR1KDM4ENPC1RAB9ASCN2A | |
| SCHEMBL7106764 | 0.76 | CNR1 (0.46) | CNR1 | |
| SCHEMBL7105213 | 0.76 | CNR2 (0.39) | CNR1KDM4ESMN1; SMN2 | |
| SCHEMBL23015758 | 0.76 | CNR1 (0.44) | CNR1KDM4ENPC1RAB9ASCN2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1001944-B1 | PYRAZINE DERIVATIVES, PREPARATION AND MEDICINES CONTAINING THEM | AVENTIS PHARMA SA (FR) | 2003-10-01 | — | — | EP | claimed |