Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 7/20 | 0.46 |
| ▸ | CNR2 | P34972 | 4/20 | 0.41 |
| ▸ | MME | P08473 | 1/20 | 0.38 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.37 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.36 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.36 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.36 |
| ▸ | GRN | P28799 | 1/20 | 0.35 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7108034 | 0.93 | CNR1 (0.44) | CNR1CNR2MMEAKR1B1S1PR3 | |
| SCHEMBL7105347 | 0.89 | CNR1 (0.46) | CNR1CNR2MMEAKR1B1SCN9A | |
| SCHEMBL7109870 | 0.81 | CNR1 (0.44) | CNR1CNR2AKR1B1S1PR3 | |
| SCHEMBL7109322 | 0.76 | SMO (0.39) | CNR1CNR2MMEMAP2K1 | |
| SCHEMBL7109193 | 0.76 | ICAM1 (0.40) | CNR2MAP2K1 | |
| SCHEMBL7103718 | 0.76 | CNR1 (0.52) | CNR1 | |
| SCHEMBL7107812 | 0.75 | POLB (0.47) | CNR1CNR2SCN9A | |
| SCHEMBL7104658 | 0.75 | SMN1; SMN2 (0.35) | CNR1 | |
| SCHEMBL7105213 | 0.73 | CNR2 (0.39) | CNR1CNR2 | |
| SCHEMBL7109282 | 0.73 | CNR1 (0.42) | CNR1CNR2AKR1B1S1PR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1001944-B1 | PYRAZINE DERIVATIVES, PREPARATION AND MEDICINES CONTAINING THEM | AVENTIS PHARMA SA (FR) | 2003-10-01 | — | — | EP | claimed |