Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRK1 | P41145 | 7/20 | 0.66 |
| ▸ | OPRD1 | P41143 | 3/20 | 0.65 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | NR3C1 | P04150 | 6/20 | 0.39 |
| ▸ | PGR | P06401 | 2/20 | 0.39 |
| ▸ | AR | P10275 | 2/20 | 0.39 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.37 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.37 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.37 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.36 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.36 |
| ▸ | MMP1 | P03956 | 1/20 | 0.36 |
| ▸ | MMP2 | P08253 | 1/20 | 0.36 |
| ▸ | MMP9 | P14780 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7106593 | 0.81 | OPRK1 (0.75) | OPRK1OPRD1NPC1OPRM1OPRL1 | |
| SCHEMBL7106995 | 0.81 | OPRK1 (0.89) | OPRK1OPRD1OPRM1OPRL1MMP1 | |
| SCHEMBL7108645 | 0.79 | OPRK1 (1.00) | OPRK1OPRD1OPRM1OPRL1MMP1 | |
| SCHEMBL7105487 | 0.77 | OPRK1 (0.64) | OPRK1OPRD1SMN1; SMN2L3MBTL1NR3C1 | |
| SCHEMBL7106355 | 0.73 | OPRK1 (1.00) | OPRK1OPRD1NPC1OPRM1MMP1 | |
| SCHEMBL7101712 | 0.67 | OPRK1 (1.00) | OPRK1OPRD1KMT2A | |
| SCHEMBL12592945 | 0.65 | NR3C1 (0.82) | NR3C1PGRAR | |
| SCHEMBL12592946 | 0.65 | NR3C1 (0.82) | NR3C1PGRAR | |
| SCHEMBL2896358 | 0.65 | NR3C1 (0.82) | NR3C1PGRAR | |
| SCHEMBL13774782 | 0.64 | OPRK1 (0.68) | OPRK1OPRD1SMN1; SMN2MEN1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1055665-B1 | 3-(3-Hydroxyphenyl)-3-amino-propionamide derivatives | PFIZER PROD INC (US) | 2003-10-22 | — | — | EP | disclosed |
| EP-1055665-A1 | 3-(3-Hydroxyphenyl)-3-amino-propionamide derivatives | Pfizer Products Inc. (US) | 2000-11-29 | — | — | EP | disclosed |