Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRK1 | P41145 | 14/20 | 1.00 |
| ▸ | OPRD1 | P41143 | 7/20 | 1.00 |
| ▸ | OPRM1 | P35372 | 7/20 | 0.51 |
| ▸ | DRD2 | P14416 | 2/20 | 0.43 |
| ▸ | DRD3 | P35462 | 2/20 | 0.43 |
| ▸ | MMP8 | P22894 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.39 |
| ▸ | MMP1 | P03956 | 1/20 | 0.39 |
| ▸ | MMP2 | P08253 | 1/20 | 0.39 |
| ▸ | MMP9 | P14780 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7106995 | 0.85 | OPRK1 (0.89) | OPRK1OPRD1OPRM1DRD2DRD3 | |
| SCHEMBL7106593 | 0.85 | OPRK1 (0.75) | OPRK1OPRD1OPRM1MMP8POLB | |
| SCHEMBL7105490 | 0.79 | OPRK1 (0.66) | OPRK1OPRD1OPRM1OPRL1MMP1 | |
| SCHEMBL7106355 | 0.76 | OPRK1 (1.00) | OPRK1OPRD1OPRM1MMP8POLB | |
| SCHEMBL7101712 | 0.70 | OPRK1 (1.00) | OPRK1OPRD1MMP8POLB | |
| SCHEMBL18375462 | 0.67 | OPRM1 (1.00) | OPRK1OPRD1OPRM1 | |
| SCHEMBL21824300 | 0.67 | OPRM1 (1.00) | OPRK1OPRD1OPRM1 | |
| SCHEMBL13774782 | 0.67 | OPRK1 (0.68) | OPRK1OPRD1MMP8POLB | |
| SCHEMBL7101012 | 0.67 | OPRK1 (1.00) | OPRK1OPRD1DRD3POLB | |
| SCHEMBL1709294 | 0.67 | POLB (0.81) | OPRK1MMP8POLBMMP1MMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1055665-B1 | 3-(3-Hydroxyphenyl)-3-amino-propionamide derivatives | PFIZER PROD INC (US) | 2003-10-22 | — | — | EP | disclosed |
| EP-1055665-A1 | 3-(3-Hydroxyphenyl)-3-amino-propionamide derivatives | Pfizer Products Inc. (US) | 2000-11-29 | — | — | EP | disclosed |