SCHEMBL7106732

SCHEMBL7106732

CCC(C)Cc1ccc(OC(C)OC2CCCCC2)cc1

nearest known ligand 0.37

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.37
ALOX12 P18054 1/20 0.37
ACACB O00763 6/20 0.36
KDM4E B2RXH2 1/20 0.35
GRM2 Q14416 4/20 0.34
PPARG P37231 1/20 0.33
PPARD Q03181 1/20 0.33
PPARA Q07869 1/20 0.33
HRH3 Q9Y5N1 2/20 0.33
HTT P42858 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14086001 0.87 ACACB (0.38) ALDH1A1ACACBKDM4EGRM2HRH3
SCHEMBL7108437 0.85 ALDH1A1 (0.38) ALDH1A1ALOX12KDM4EGRM2PPARG
SCHEMBL23907146 0.84 LTA4H (0.41) ALDH1A1ALOX12KDM4EGRM2HRH3
SCHEMBL7102645 0.83 KMT2A (0.42) ALDH1A1ACACBKDM4EPPARGPPARA
SCHEMBL825446 0.80 ALDH1A1 (0.43) ALDH1A1KDM4EHTT
SCHEMBL26015195 0.79 ALDH1A1 (0.36) ALDH1A1ALOX12ACACBKDM4EGRM2
SCHEMBL14838227 0.79 HTT (0.44) ALDH1A1ACACBKDM4EGRM2HRH3
SCHEMBL23907136 0.79 KDM4E (0.39) ALDH1A1ALOX12KDM4EGRM2
SCHEMBL2607766 0.78 ALDH1A1 (0.43) ALDH1A1KDM4E
SCHEMBL23907079 0.78 LTA4H (0.40) ALDH1A1ALOX12KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1113005-B1 Sulfonium salt compounds WAKO PURE CHEM IND LTD (JP) 2003-08-06 EP disclosed
EP-1238969-A2 Sulfonium salt compounds Wako Pure Chemical Industries, Ltd. (JP) 2002-09-11 EP disclosed
EP-1113005-A1 Sulfonium salt compounds Wako Pure Chemical Industries, Ltd. (JP) 2001-07-04 EP disclosed