Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MC4R | P32245 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | DGAT2 | Q96PD7 | 1/20 | 0.35 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.35 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5776703 | 0.86 | P2RX3 (0.46) | — | |
| SCHEMBL5777006 | 0.76 | SMN1; SMN2 (0.44) | MC4RMEN1KMT2ANOTUMALDH1A1 | |
| SCHEMBL18584701 | 0.75 | ABHD6 (0.43) | MEN1KMT2ANOTUMRAB9ANLRP3 | |
| SCHEMBL16268894 | 0.74 | S1PR5 (0.40) | MEN1KMT2ANOTUMRAB9ANLRP3 | |
| SCHEMBL28901639 | 0.74 | ABHD6 (0.41) | MEN1KMT2ANOTUMRAB9ANLRP3 | |
| SCHEMBL5773712 | 0.73 | CD44 (0.41) | KCNH2MEN1KMT2A | |
| SCHEMBL5776465 | 0.73 | CYP2A13 (0.44) | ALDH1A1 | |
| SCHEMBL5774994 | 0.72 | KDM4E (0.41) | KMT2ANOTUMRAB9AALDH1A1 | |
| SCHEMBL28245902 | 0.72 | S1PR5 (0.51) | MEN1KMT2ANOTUM | |
| SCHEMBL5775730 | 0.72 | KDM4E (0.39) | MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1483257-A1 | QUINAZOLINE COMPOUNDS USEFUL IN THERAPY | Pfizer Limited (GB) | 2004-12-08 | — | — | EP | disclosed |
| WO-2003076427-A1 | QUINAZOLINE COMPOUNDS USEFUL IN THERAPY | PFIZER LIMITED (GB) | 2003-09-18 | — | — | WO | disclosed |