Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.57 |
| ▸ | HPGD | P15428 | 5/20 | 0.53 |
| ▸ | GAA | P10253 | 2/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.47 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.43 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA7 | P43166 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.42 |
| ▸ | NAMPT | P43490 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20203666 | 1.00 | ALDH1A1 (0.57) | ALDH1A1HPGDGAATSHRHSD17B10 | |
| SCHEMBL10202307 | 0.94 | ALDH1A1 (0.50) | ALDH1A1HPGDGAATSHRHSD17B10 | |
| SCHEMBL14930583 | 0.94 | ALDH1A1 (0.50) | ALDH1A1HPGDGAATSHRHSD17B10 | |
| SCHEMBL7478058 | 0.94 | ALDH1A1 (0.50) | ALDH1A1HPGDGAATSHRHSD17B10 | |
| SCHEMBL16077992 | 0.82 | ALDH1A1 (0.56) | ALDH1A1HPGDGAATSHRHSD17B10 | |
| SCHEMBL22047940 | 0.82 | ALDH1A1 (0.55) | ALDH1A1HPGDGAATSHRHSD17B10 | |
| SCHEMBL13873135 | 0.79 | ALDH1A1 (0.53) | ALDH1A1HPGDGAATSHRHSD17B10 | |
| SCHEMBL14635889 | 0.79 | ALDH1A1 (0.53) | ALDH1A1HPGDGAATSHRHSD17B10 | |
| SCHEMBL4028484 | 0.79 | HPGD (0.60) | ALDH1A1HPGDGAATSHRSMN1; SMN2 | |
| SCHEMBL14439211 | 0.77 | HPGD (0.58) | ALDH1A1HPGDGAASMN1; SMN2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030139427-A1 | Bicyclic pyrimidinyl derivatives and methods of use thereof | OSI PHARMACEUTICALS INC. | 2003-07-24 | — | — | US | claimed |
| EP-3356345-B1 | HETEROARYL DERIVATIVES AS SEPIAPTERIN REDUCTASE INHIBITORS | MAX PLANCK GESELLSCHAFT (DE) | 2023-11-08 | — | — | EP | disclosed |
| US-10779540-B2 | Benzamide compounds and their use as herbicides | BASF SE (DE) | 2020-09-22 | — | — | US | disclosed |
| EP-3390372-B1 | BENZAMIDE COMPOUNDS AND THEIR USE AS HERBICIDES | BASF SE (DE) | 2020-06-03 | — | — | EP | disclosed |
| WO-2017102275-A1 | BENZAMIDE COMPOUNDS AND THEIR USE AS HERBICIDES | BASF SE (DE) | 2017-06-22 | — | — | WO | disclosed |
| US-20030139427-A1 | Bicyclic pyrimidinyl derivatives and methods of use thereof | OSI PHARMACEUTICALS INC. | 2003-07-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10779540-B2 | Benzamide compounds and their use as herbicides | DDT, DNPH1, BBOX1 | ALDH1A1 74/4885HPGD 907/4885GAA 421/4885 |
| US-20030139427-A1 | Bicyclic pyrimidinyl derivatives and methods of use thereof | ADORA2A, ADORA3, ADORA1 | ALDH1A1 417/4885HPGD 2007/4885GAA 1734/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.