SCHEMBL7107948

SCHEMBL7107948

Cc1ccc(-c2ccccc2)cc1S(=O)(=O)c1cc(-c2ccccc2)ccc1C

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOB P27338 1/20 0.50
HTR6 P50406 1/20 0.47
POLB P06746 2/20 0.43
KDM4E B2RXH2 2/20 0.43
CYP3A4 P08684 1/20 0.43
CYP2C9 P11712 1/20 0.43
TNKS2 Q9H2K2 1/20 0.42
MAPT P10636 2/20 0.41
SMN1; SMN2 Q16637 2/20 0.41
MEN1 O00255 2/20 0.41
KMT2A Q03164 2/20 0.41
APAF1 O14727 1/20 0.41
NPC1 O15118 1/20 0.41
LMNA P02545 1/20 0.41
THRB P10828 1/20 0.41
XBP1 P17861 1/20 0.41
PTBP1 P26599 1/20 0.41
HTT P42858 1/20 0.41
RAB9A P51151 1/20 0.41
GALK1 P51570 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4843096 0.85 MAOB (0.48) MAOBHTR6POLBTNKS2MAPT
SCHEMBL4135815 0.84 HTR6 (0.51) MAOBHTR6POLBKDM4ECYP3A4
SCHEMBL31464171 0.82 MAOB (0.46) MAOBHTR6POLBKDM4ECYP3A4
SCHEMBL18518031 0.82 MAOB (0.44) MAOBHTR6KDM4ETNKS2MAPT
SCHEMBL13321733 0.80 HTR6 (0.49) HTR6POLBKDM4ECYP3A4MAPT
SCHEMBL9298222 0.76 ALOX5 (0.57) POLBKDM4EMAPTMEN1KMT2A
SCHEMBL4402282 0.75 ALDH1A1 (0.53) HTR6POLBKDM4ECYP3A4MAPT
SCHEMBL28053976 0.74 MMP1 (0.55) HTR6POLBKDM4ECYP3A4CYP2C9
SCHEMBL16639428 0.74 LMNA (0.45) MAOBHTR6POLBKDM4ECYP3A4
SCHEMBL11781981 0.74 CA12 (0.50) CYP2C9CA12CA2CA9CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1330629-C Integrated process for the preparation of aromatic isocyanates and procedures for effecting the relative intermediate phases ENICHEM SPA (US) 2007-08-08 CN disclosed
EP-0794218-B1 Polycarbonate resin composition stabilized against radiation MITSUBISHI ENG PLASTICS CORP (JP) 2003-10-15 EP disclosed
EP-0753540-B1 Polycarbonate resin composition MITSUBISHI ENG PLASTICS CORP (JP) 2003-06-11 EP disclosed
US-6359028-B1 USED IN MEDICAL EQUIPMENT, DISCOLORATION INHIBITION MITSUBISHI ENGINEERING-PLASTICS CORPORATION (JP) 2002-03-19 US disclosed
US-6040367-A EXCELLENT RESISTANCE TO AN IONIZING RADIATION, IN WHICH HETEROCYCLIC COMPOUND CONTAINING OXYMETHYLENE UNITS MITSUBISHI ENGINEERING-PLASTICS CORPORATION (JP) 2000-03-21 US disclosed
US-5977206-A Polycarbonate resin composition MITSUBISHI ENGINEERING-PLASTICS CORP. (JP) 1999-11-02 US disclosed
US-5948838-A 0.01 TO 5 PARTS BY WEIGHT OF A COMPOUND CONTAINING OXYMETHYLENE UNIT MITSUBISHI ENGINEERING-PLASTICS CORP. (JP) 1999-09-07 US disclosed
EP-0794218-A2 Polycarbonate resin composition stabilized against radiation MITSUBISHI ENGINEERING-PLASTICS CORPORATION (JP) 1997-09-10 EP disclosed
EP-0753540-A2 Polycarbonate resin composition MITSUBISHI ENGINEERING-PLASTICS CORPORATION (JP) 1997-01-15 EP disclosed
US-3948788-A DIARYL SULFONES, HALOGEN-FREE AROMATIC COMPOUNDS MONSANTO COMPANY (US) 1976-04-06 US disclosed
US-3948787-A DIARYL SULFONES, CARBOXYLIC ESTERS MONSANTO COMPANY (US) 1976-04-06 US disclosed