Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR2 | O95136 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | RXRA | P19793 | 9/20 | 0.35 |
| ▸ | RXRB | P28702 | 8/20 | 0.35 |
| ▸ | RXRG | P48443 | 6/20 | 0.35 |
| ▸ | ATF1 | P18846 | 1/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.33 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | GRM5 | P41594 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2092292 | 0.78 | TPMT (0.44) | SMN1; SMN2ALDH1A1RXRARXRBRXRG | |
| SCHEMBL1400929 | 0.77 | ALDH1A1 (0.46) | ALDH1A1POLBKDM4EFFAR1KMT2A | |
| SCHEMBL21816685 | 0.77 | MAPT (0.40) | SMN1; SMN2ALDH1A1MAPK1POLBKDM4E | |
| SCHEMBL2097580 | 0.77 | POLB (0.39) | SMN1; SMN2ALDH1A1POLB | |
| SCHEMBL15595426 | 0.74 | PAX8 (0.44) | S1PR2RXRARXRBRXRGATF1 | |
| SCHEMBL8551879 | 0.72 | APP (0.41) | S1PR2ALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL23060418 | 0.72 | ATF1 (0.37) | S1PR2SMN1; SMN2RXRARXRBRXRG | |
| SCHEMBL465570 | 0.71 | TPMT (0.46) | ALDH1A1RXRARXRBRXRGKDM4E | |
| SCHEMBL26624101 | 0.71 | ATF1 (0.36) | S1PR2RXRARXRBRXRGATF1 | |
| SCHEMBL21551640 | 0.71 | RAB9A (0.42) | SMN1; SMN2ALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3166945-B1 | NOVEL TRIAZOLOPYRIMIDINONE OR TRIAZOLOPYRIDINONE DERIVATIVES, AND USE THEREOF | ST PHARM CO LTD (KR) | 2019-10-09 | — | — | EP | disclosed |
| US-9914737-B2 | Triazolopyrimidinone or triazolopyridinone derivatives, and use thereof | ST PHARM CO., LTD. (KR) | 2018-03-13 | — | — | US | disclosed |
| US-20170145016-A1 | NOVEL TRIAZOLOPYRIMIDINONE OR TRIAZOLOPYRIDINONE DERIVATIVES, AND USE THEREOF | ST PHARM CO., LTD. (KR) | 2017-05-25 | — | — | US | disclosed |
| EP-3166945-A2 | NOVEL TRIAZOLOPYRIMIDINONE OR TRIAZOLOPYRIDINONE DERIVATIVES, AND USE THEREOF | ST Pharm Co. Ltd. (KR) | 2017-05-17 | — | — | EP | disclosed |
| WO-2016006974-A2 | NOVEL TRIAZOLOPYRIMIDINONE OR TRIAZOLOPYRIDINONE DERIVATIVES, AND USE THEREOF | ST PHARM CO., LTD. (KR) | 2016-01-14 | — | — | WO | disclosed |
| EP-1345494-A2 | DICHLOROPYRIDYL METHYLAMIDES | Bayer CropScience AG (DE) | 2003-09-24 | — | — | EP | disclosed |
| WO-2002050035-A2 | INSECTICIDAL AND FUNGICIDAL (2,6-DICHLORO-4-PYRIDYL) METHYLCARBAMATES USED AS PLANT PROTECTIVE AGENTS | BAYER CROPSCIENCE AG (DE) | 2002-06-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170145016-A1 | NOVEL TRIAZOLOPYRIMIDINONE OR TRIAZOLOPYRIDINONE DERIVATIVES, AND USE THEREOF | TNKS1BP1, TNKS, TPI1 | S1PR2 3942/4885SMN1; SMN2 1022/4885ALDH1A1 2244/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.