SCHEMBL7108620

SCHEMBL7108620

N#COc1cc2ccccc2c(O)c1Cl

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 1/20 0.36
CA2 P00918 1/20 0.36
PTPN22 Q9Y2R2 1/20 0.35
TRPM4 Q8TD43 1/20 0.35
KDM4E B2RXH2 1/20 0.35
MEN1 O00255 1/20 0.35
ALDH1A1 P00352 1/20 0.35
GAA P10253 1/20 0.35
MAPT P10636 1/20 0.35
CACNA1B Q00975 1/20 0.35
APBA1 Q02410 1/20 0.35
KMT2A Q03164 1/20 0.35
CASP6 P55212 1/20 0.35
NQO2 P16083 1/20 0.34
NQO1 P15559 1/20 0.34
ERN1 O75460 1/20 0.32
CYP2A6 P11509 1/20 0.32
LMNA P02545 1/20 0.31
NCEH1 Q6PIU2 1/20 0.31
ESR1 P03372 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23043242 0.78 NQO1 (0.46) KDM4EMEN1ALDH1A1GAAMAPT
SCHEMBL30707088 0.78 NQO1 (0.46) KDM4EMEN1ALDH1A1GAAMAPT
SCHEMBL7106897 0.76 PTPN22 (0.48) PTPN22KDM4EMEN1ALDH1A1GAA
Cyanate SCHEMBL7109909 0.75 HPGD (0.40) CA1CA2PTPN22TRPM4KDM4E
SCHEMBL1325698 0.73 GPR84 (0.36) CA1CA2TRPM4ALDH1A1NQO2
SCHEMBL28065752 0.72 CYP2A6 (0.39) CA1CA2KDM4EALDH1A1GAA
SCHEMBL29936999 0.72 CLCN2 (0.37) PTPN22ERN1
SCHEMBL7109906 0.71 MEN1 (0.42) KDM4EMEN1ALDH1A1GAAMAPT
SCHEMBL554286 0.71 HSD17B10 (0.48) PTPN22TRPM4KDM4EMEN1ALDH1A1
SCHEMBL30499577 0.71 HSD17B10 (0.48) PTPN22TRPM4KDM4EMEN1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6458993-B1 AROMATIC CYANATE ESTER COMPOUNDS HAVING AT LEAST TWO RINGS LINKED BY AN UNSATURATED GROUP CONTAINING MEMBER CAN BE EMPLOYED IN ADHESIVES, COMPOSITES, LAMINATES AND MOLDINGS VANTICO INC. 2002-10-01 US claimed
US-20020055648-A1 Cyanate esters having flame resistant properties JPMORGAN CHASE BANK, N.A. 2002-05-09 US claimed
EP-1161414-B1 CYANATE ESTERS HAVING FLAME RESISTANT PROPERTIES VANTICO AG (CH) 2003-10-01 EP disclosed
US-6458993-B1 AROMATIC CYANATE ESTER COMPOUNDS HAVING AT LEAST TWO RINGS LINKED BY AN UNSATURATED GROUP CONTAINING MEMBER CAN BE EMPLOYED IN ADHESIVES, COMPOSITES, LAMINATES AND MOLDINGS VANTICO INC. 2002-10-01 US disclosed
US-20020055648-A1 Cyanate esters having flame resistant properties JPMORGAN CHASE BANK, N.A. 2002-05-09 US disclosed
EP-1161414-A1 CYANATE ESTERS HAVING FLAME RESISTANT PROPERTIES Vantico AG (CH) 2001-12-12 EP disclosed
US-6242638-B1 FIREPROOFING USING CURED MIXTURES VANTICO INC. 2001-06-05 US disclosed
WO-2000055123-A1 CYANATE ESTERS HAVING FLAME RESISTANT PROPERTIES VANTICO AG (CH) 2000-09-21 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020055648-A1 Cyanate esters having flame resistant properties PCCA, FABP4, MCCC2 CA1 2751/4885CA2 1342/4885PTPN22 4461/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.