Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.41 |
| ▸ | BACE1 | P56817 | 2/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.40 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.40 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.38 |
| ▸ | F2RL1 | P55085 | 1/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | CLPP | Q16740 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25382340 | 0.89 | MMP8 (0.41) | RAB9AALDH1A1OPRM1OPRD1OPRK1 | |
| SCHEMBL30565292 | 0.89 | MMP8 (0.41) | RAB9AALDH1A1OPRM1OPRD1OPRK1 | |
| SCHEMBL29456772 | 0.89 | MMP8 (0.41) | RAB9AALDH1A1OPRM1OPRD1OPRK1 | |
| SCHEMBL30482920 | 0.86 | F2RL1 (0.41) | RAB9AALDH1A1BACE1OPRM1OPRD1 | |
| SCHEMBL30482923 | 0.86 | F2RL1 (0.41) | RAB9AALDH1A1BACE1OPRM1OPRD1 | |
| SCHEMBL28861768 | 0.80 | BACE1 (0.47) | RAB9AALDH1A1BACE1OPRM1OPRD1 | |
| SCHEMBL11243260 | 0.79 | PDF (0.43) | RAB9AALDH1A1ALOX12BACE1SMN1; SMN2 | |
| SCHEMBL1393531 | 0.78 | OPRD1 (0.36) | RAB9ABACE1OPRM1OPRD1OPRK1 | |
| SCHEMBL9329807 | 0.77 | BACE1 (0.49) | RAB9ABACE1SMN1; SMN2NPC1TP53 | |
| SCHEMBL5680168 | 0.76 | BACE1 (0.36) | RAB9AALDH1A1ALOX12BACE1OPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250170104-A1 | INHIBITORS OF PSEUDOMONAS AERUGINOSA VIRULENCE FACTOR Lasß | HELMHOLTZ ZENTRUM INFEKTIONSFORSCHUNG GMBH (DE) | 2025-05-29 | — | — | US | disclosed |
| WO-2023166039-A1 | INHIBITORS OF PSEUDOMONAS AERUGINOSA VIRULENCE FACTOR Lasß | Helmholtz-Zentrum für Infektionsforschung GmbH (DE) | 2023-09-07 | — | — | WO | disclosed |
| EP-3475260-B1 | COMPOUNDS FOR USE AS AN ANTI-BACTERIAL OR ANTI-FUNGAL AGENT AND AS A ZINC SENSOR | UNIV KONSTANZ (DE) | 2022-03-30 | — | — | EP | disclosed |
| US-10961196-B2 | Compounds for use as an anti-bacterial or anti-fungal agent and as a zinc sensor | Universität Konstanz (DE) | 2021-03-30 | — | — | US | disclosed |
| US-20190218183-A1 | COMPOUNDS FOR USE AS AN ANTI-BACTERIAL OR ANTI-FUNGAL AGENT AND AS A ZINC SENSOR | Universität Konstanz (DE) | 2019-07-18 | — | — | US | disclosed |
| EP-3475260-A1 | COMPOUNDS FOR USE AS AN ANTI-BACTERIAL OR ANTI-FUNGAL AGENT AND AS A ZINC SENSOR | Universität Konstanz (DE) | 2019-05-01 | — | — | EP | disclosed |
| WO-2017220205-A1 | COMPOUNDS FOR USE AS AN ANTI-BACTERIAL OR ANTI-FUNGAL AGENT AND AS A ZINC SENSOR | Universität Konstanz (DE) | 2017-12-28 | — | — | WO | disclosed |
| EP-3260445-A1 | COMPOUNDS FOR USE AS AN ANTI-BACTERIAL OR ANTI-FUNGAL AGENT AND AS A ZINC SENSOR | Universität Konstanz (DE) | 2017-12-27 | — | — | EP | disclosed |
| EP-1019434-B1 | INHIBITORS OF METALLOPROTEINASES, THEIR THERAPEUTIC USE, AND PROCESS FOR THE PRODUCTION OF THE STARTING COMPOUND IN THEIR SYNTHESIS | POLIFARMA SPA (IT) | 2003-10-01 | — | — | EP | disclosed |
| US-6339160-B1 | FOR THERAPY OF TUMORAL GROWTH AND METASTATIZATION, ATEROSCLEROSIS, MULTIPLE SCLEROSIS, ALZHEIMER'S DISEASE, OSTEOPOROSIS, HYPERTENSION, RHEUMATOID ARTHRITIS AND OTHER INFLAMMATORY DISEASES | POLIFARMA S.P.A. (IT) | 2002-01-15 | — | — | US | disclosed |
| EP-1019434-A2 | INHIBITORS OF METALLOPROTEINASES, THEIR THERAPEUTIC USE, AND PROCESS FOR THE PRODUCTION OF THE STARTING COMPOUND IN THEIR SYNTHESIS | POLIFARMA S.p.A. (IT) | 2000-07-19 | — | — | EP | disclosed |
| WO-1999003878-A2 | INHIBITORS OF METALLOPROTEINASES, THEIR THERAPEUTIC USE, AND PROCESS FOR THE PRODUCTION OF THE STARTING COMPOUND IN THEIR SYNTHESIS | POLIFARMA S.P.A. (IT) | 1999-01-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190218183-A1 | COMPOUNDS FOR USE AS AN ANTI-BACTERIAL OR ANTI-FUNGAL AGENT AND AS A ZINC SENSOR | ZFR, ZC3HAV1, ZFX | RAB9A 3657/4885ALDH1A1 4356/4885ALOX12 2714/4885 |
| US-10961196-B2 | Compounds for use as an anti-bacterial or anti-fungal agent and as a zinc sensor | ZFR, ZC3HAV1, ZFX | RAB9A 3657/4885ALDH1A1 4356/4885ALOX12 2714/4885 |
| US-20250170104-A1 | INHIBITORS OF PSEUDOMONAS AERUGINOSA VIRULENCE FACTOR Lasß | LTA, SERPINB1, LAS1L | RAB9A 1219/4885ALDH1A1 3061/4885ALOX12 47/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.