Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE known ✓ | P22303 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | BCHE | P06276 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7108565 | 0.80 | BCHE (0.41) | ALDH1A1MEN1KMT2ABCHEACHE | |
| Hydrochloric Acid SCHEMBL6865136 | 0.79 | ACHE (0.39) | BCHEACHEL3MBTL1 | |
| Hydrochloric Acid SCHEMBL5855314 | 0.77 | MAPK1 (0.44) | ALDH1A1MEN1KMT2ABCHEACHE | |
| Hydrochloric Acid SCHEMBL5853633 | 0.75 | KMT2A (0.35) | KDM4EMEN1KMT2ABCHEACHE | |
| Hydrochloric Acid SCHEMBL5854750 | 0.72 | NPSR1 (0.39) | ALDH1A1KDM4EHTTMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL5852985 | 0.71 | SOAT1 (0.43) | ALDH1A1HTTMEN1KMT2APOLB | |
| Hydrochloric Acid SCHEMBL5853249 | 0.70 | SOAT1 (0.44) | ALDH1A1MEN1KMT2APOLB | |
| Hydrochloric Acid SCHEMBL5855548 | 0.70 | SOAT1 (0.44) | ALDH1A1MEN1KMT2APOLB | |
| Hydrochloric Acid SCHEMBL7108775 | 0.70 | KDM4E (0.35) | ALDH1A1KDM4E | |
| Hydrochloric Acid SCHEMBL5853050 | 0.69 | ALOX5 (0.38) | ALDH1A1KDM4EHTTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004106394-A1 | COPOLYMERS OF ETHYLENE AND/OR α-OLEFINS AND VICINALLY DISUBSTITUTED OLEFINS | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2004-12-09 | — | — | WO | disclosed |