Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | ALPG | P10696 | 1/20 | 0.47 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.47 |
| ▸ | HTR1A | P08908 | 1/20 | 0.47 |
| ▸ | DRD2 | P14416 | 1/20 | 0.47 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.46 |
| ▸ | CDK1 | P06493 | 1/20 | 0.46 |
| ▸ | CDK4 | P11802 | 1/20 | 0.46 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.46 |
| ▸ | CCND1 | P24385 | 1/20 | 0.46 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.46 |
| ▸ | LIPE | Q05469 | 1/20 | 0.46 |
| ▸ | MGLL | Q99685 | 1/20 | 0.46 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.45 |
| ▸ | LTA4H | P09960 | 1/20 | 0.45 |
| ▸ | ACLY | P53396 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6749805 | 0.90 | MEN1 (0.48) | MAPTL3MBTL1MAPK1TDP1HPGD | |
| SCHEMBL6745587 | 0.86 | FFAR1 (0.48) | MAPTL3MBTL1MAPK1TDP1HPGD | |
| SCHEMBL7108877 | 0.85 | MAPT (0.53) | MAPTL3MBTL1MAPK1TDP1ALPG | |
| SCHEMBL5679038 | 0.83 | CA1 (0.46) | HPGDCA1CA2CA9CA12 | |
| SCHEMBL1028419 | 0.82 | ALPG (0.51) | MAPTL3MBTL1MAPK1TDP1ALPG | |
| SCHEMBL4164605 | 0.82 | MAPT (0.55) | MAPTL3MBTL1MAPK1TDP1ALPG | |
| SCHEMBL1013565 | 0.82 | CA1 (0.56) | MAPTL3MBTL1MAPK1TDP1ALPG | |
| SCHEMBL27688885 | 0.81 | PTGER1 (0.47) | MAPTL3MBTL1MAPK1TDP1PTGER1 | |
| SCHEMBL7267144 | 0.81 | MAPT (0.49) | MAPTL3MBTL1MAPK1TDP1ALPG | |
| SCHEMBL14842559 | 0.80 | FABP4 (0.50) | MAPTL3MBTL1MAPK1TDP1ALPG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 61 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250122182-A1 | MYST Inhibitors | Isosterix, Inc. | 2025-04-17 | — | — | US | disclosed |
| EP-1892239-B1 | Inhibitors of cytosolic phospholipase A2 | WYETH LLC (US) | 2013-02-20 | — | — | EP | disclosed |
| CN-101628888-B | Inhibitors of cytosolic phospholipase a2 | WYETH CORP | 2012-05-23 | — | — | CN | disclosed |
| US-8163773-B2 | Organic compounds | NOVARTIS AG (CH) | 2012-04-24 | — | — | US | disclosed |
| US-7906548-B2 | Methods for the use of inhibitors of cytosolic phospholipase A2 | WYETH LLC (US) | 2011-03-15 | — | — | US | disclosed |
| US-7713964-B2 | Methods for treating asthmatic conditions | WYETH LLC (US) | 2010-05-11 | — | — | US | disclosed |
| US-20100035957-A1 | Methods for the Use of Inhibitors of Cytosolic Phospholipase A2 | WYETH | 2010-02-11 | — | — | US | disclosed |
| CN-101628888-A | Inhibitors of cytosolic phospholipase A2 | WYETH CORP | 2010-01-20 | — | — | CN | disclosed |
| US-7605156-B2 | Methods for the use of inhibitors of cytosolic phospholipase A2 | WYETH (US) | 2009-10-20 | — | — | US | disclosed |
| US-20090233920-A1 | ORGANIC COMPOUNDS | NOVARTIS AG (CH) | 2009-09-17 | — | — | US | disclosed |
| EP-0934291-A4 | — | SMITHKLINE BEECHAM CORP (US) | 1999-08-11 | — | — | EP | disclosed |
| EP-0934291-A1 | PROTEASE INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 1999-08-11 | — | — | EP | disclosed |
| CN-1207095-A | Protease inhibitors | SMITHKLINE BEECHAM CORP (US) | 1999-02-03 | — | — | CN | disclosed |
| EP-0687253-B1 | 4-AMINOPYRIDINES, PROCESS FOR PREPARING THE SAME AND MEDICAMENTS CONTAINING THE SAME | BOEHRINGER MANNHEIM GMBH (DE) | 1998-12-16 | — | — | EP | disclosed |
| WO-1997016433-A1 | PROTEASE INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 1997-05-09 | — | — | WO | disclosed |
| CN-1119858-A | Aminopyridines, process for their preparation and pharmaceutical compositions containing them | BOEHRINGER MANNHEIM GMBH (DE) | 1996-04-03 | — | — | CN | disclosed |
| EP-0687253-A1 | NEW 4-AMINOPYRIDINES, PROCESS FOR PREPARING THE SAME AND MEDICAMENTS CONTAINING THE SAME | Roche Diagnostics GmbH (DE) | 1995-12-20 | — | — | EP | disclosed |
| WO-1994020467-A1 | NEW 4-AMINOPYRIDINES, PROCESS FOR PREPARING THE SAME AND MEDICAMENTS CONTAINING THE SAME | BOEHRINGER MANNHEIM GMBH (DE) | 1994-09-15 | — | — | WO | disclosed |
| US-4829079-A | AMNESIA | ROUSSEL UCLAF (FR) | 1989-05-09 | — | — | US | disclosed |
| US-4425153-A | Herbicidal sulfonamides | E. I. DU PONT DE NEMOURS & CO. (US) | 1984-01-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090233920-A1 | ORGANIC COMPOUNDS | REN, ACE, AGTR1 | MAPT 1008/4885L3MBTL1 3191/4885MAPK1 3136/4885 |
| US-20250122182-A1 | MYST Inhibitors | MNAT1, SUGT1, ACAT2 | MAPT 476/4885L3MBTL1 1245/4885MAPK1 1355/4885 |
| US-20100035957-A1 | Methods for the Use of Inhibitors of Cytosolic Phospholipase A2 | PLA2G4A, PLA2G4B, PLA2G1B | MAPT 3957/4885L3MBTL1 3369/4885MAPK1 1566/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.